Results 91 to 100 of about 21,454 (214)

Treatment of Autosomal-Dominant Polycystic Kidney Disease

American Journal of Kidney Diseases
Autosomal-dominant polycystic kidney disease (ADPKD) is a chronic systemic disease that affects all races and ethnicities. It is the fourth leading cause of end-stage kidney disease, and it has a heterogenous phenotype ranging from mild to severe disease.
Sara S, Jdiaa, Reem A, Mustafa, Alan S L, Yu   +2 more
openaire   +2 more sources

Investigating TRPM3 Modulation and Cyst Reversibility in Ex Vivo and Organoid Models of Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disease, affecting approximately 1 in 1000 live births. It is characterised by multiple fluid-filled cysts in renal tubules.
Gul, Huseyin
core   +2 more sources

Autophagy and Autosomal Dominant Polycystic Kidney Disease

Turkish Journal of Nephrology, 2023
Özgür Akın Oto, Charles L. Edelstein
doaj   +1 more source

CALCIUM HOMEOSTASIS AND POLYCYSTIN-2 EXPRESSION IN T-LYMPHOBLASTS OF PKD SUBJECTS

, 2009
Mutations of polycystin-1 (PC1) and polycystin-2 (PC2), coded by PKD1 and PKD2 genes, account for approximately 85 and 15% of Autosomal Dominant Polycystic Kidney Disease (ADPKD) cases, a common and important inherited kidney disorder.
Durante, Chiara
core  

Renal Transplantation in Autosomal Dominant Polycystic Kidney Disease [PDF]

European Medical Journal Nephrology, 2015
Autosomal dominant polycystic kidney disease (ADPKD) affects approximately 1 in 1,000 people in the general population. The natural history of ADPKD includes the progression of chronic kidney disease to end-stage renal disease (ESRD) in a large ...
Andrzej Kulesza, Longin Niemczyk, Mariusz Niemczyk   +2 more
doaj  

Epigenetics and autosomal dominant polycystic kidney disease

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2011
The roles of epigenetic modulation of gene expression and protein functions in autosomal dominant polycystic kidney disease (ADPKD) have recently become the focus of scientific investigation. Evidence generated to date indicates that one of the epigenetic modifiers, histone deacetylases (HDACs), are important regulators of ADPKD.
openaire   +2 more sources

The Effect of Autosomal Dominant Polycystic Kidney Disease on Spirometric Parameters

, 2020
Aim:There is no enough data on pulmonary involvement in autosomal dominant polycystic kidney disease (ADPKD). The aim of this study is to examine pulmonary function test in patients with ADPKD with varying stages of renal function and to compare them ...
Ozturk, Savaş, Gülfidan Çakmak, Sari, Mustafa, Zeynep Karaali, Mustafa Sarı, Cakmak, Gulfidan, Karandere, Faruk, Doner, Baris, Faruk Karandere, Barış Döner, Savaş Öztürk, GÜRSU, Meltem, Sumnu, Abdullah, Cebeci, Egemen, Meltem Gürsu, Abdullah Şumnu, Ozler, Tuba Elif, Egemen Cebeci, Tuba Elif Özler, Karaali, Zeynep   +19 more
core   +1 more source

HYPERTENSION IN AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE

Turkish Journal of Nephrology, 2019
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Züleyha AKKAN, Tevfık ECDER
doaj  

Activation of PIEZO1 Attenuates Kidney Cystogenesis In Vitro and Ex Vivo

Kidney360
Key Points. PIEZO1 activation reduces cystogenesis: Yoda1 activates PIEZO1, raising calcium and lowering cAMP, reducing cyst growth in autosomal dominant polycystic kidney disease models.
Qingfeng Fan, Mohamad Hadla, Zack Peterson, Grace Nelson, Hong Ye, Xiaofang Wang, Jean Marc Mardirossian, Peter C. Harris, Seth L. Alper, Y.S. Prakash, Arthur Beyder, Vicente E. Torres, Fouad T. Chebib   +12 more
doaj   +1 more source

Congenital hepatic fibrosis in autosomal-dominant polycystic kidney disease

, 1990
Congenital hepatic fibrosis in autosomal-dominant polycystic kidney disease. Congenital hepatic fibrosis was found in four families with autosomal-dominant polycystic kidney disease.
COBBEN, JM, ZERRES, K, Cobben, Jan M., SCHOOTS, C, Schoots, Coen, ten Kate, Leo P., BREUNING, MH, TENKATE, LP, Zerres, Klaus, Breuning, Martijn H.   +9 more
core   +1 more source