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Autosomal dominant polycystic kidney disease (ADPKD) and autosomal dominant polycystic liver disease (ADPLD) are inherited cystic conditions with overlapping features but distinct genetic causes and clinical courses.
Anna Katya Brossart +4 more
doaj +1 more source
The average weight of a kidney is approximately 135 gm, measuring on average 10 × 6 × 4 cm. In hereditary conditions, autosomal dominant and autosomal recessive polycystic kidney disease, the shape, size, and the weight can be significantly abnormal ...
Anup Hazra +3 more
doaj +1 more source
Intracranial aneurysms in autosomal dominant polycystic kidney disease [PDF]
Background The incidence of intracranial aneurysms (ICA) is high in patients with autosomal dominant polycystic kidney disease (ADPKD). However, little is known regarding the optimal screening and treatment methods for ICA.
Jung Hyun Park
doaj +1 more source
We describe an autopsy case of a 45-year-old male diagnosed with autosomal dominant polycystic kidney disease who presented with complaints of altered sensorium.
Arpitha Kollabathula +6 more
doaj +1 more source
Autosomal dominant polycystic kidney disease in Toronto
This study describes the Toronto, Ontario experience with autosomal dominant polycystic kidney disease (ADPKD). Patients were divided into three groups: Group 1, 19 families studied with genetic markers; Group 2, 80 pre-dialysis ADPKD patients followed by Toronto nephrologists in whom the incidence of non-renal complications and the mean age of onset ...
Roscoe, Janet M. +4 more
openaire +2 more sources
During kidney aging, loss of the MICOS complex drives cristae disorganization, impairs oxidative capacity, and alters mitochondrial dynamics. MICOS disruption elevates mitochondrial ROS and disrupts calcium homeostasis, linking mitochondrial structural remodeling to metabolic dysfunction in aging kidney tissue.
Prasanna Katti +48 more
wiley +1 more source
Autosomal dominant polycystic kidney disease in children [PDF]
Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary renal disease, affecting one in 500 individuals. The cardinal manifestation of ADPKD is progressive cystic dilatation of renal tubules with kidney enlargement and progression to end-stage renal disease in approximately half of cases by 60 years of age.
openaire +2 more sources
Impact of Expanded Hemodialysis on Inflammation and Iron Metabolism in Chronic Hemodialysis Patients
ABSTRACT Microinflammation and functional iron deficiency are major contributors to anemia and treatment burden in maintenance hemodialysis (HD). Medium cutoff (MCO) membranes enhance the removal of middle‐ and large‐sized solutes implicated in these pathways, yet real‐world data using routinely measured inflammatory and iron‐related markers are scarce.
Berrak Itır Aylı +2 more
wiley +1 more source
Abstract Chronic volume overload is a major risk factor of hypertension and mortality in chronic dialysis patients. However, the mechanisms responsible for hypertension are unclear. We studied 32 patients (age 23–68 years, 19 females) in chronic hemodiafiltration classified by their interdialytic ambulatory blood pressure (idABP, mmHg) in three groups:
Adolfo Diaz +5 more
wiley +1 more source
Autosomal Dominant Polycystic Kidney Disease: Review and Management Update
Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited nephropathy. Initially, it is characterised by the growth of renal cysts. Later, progressive deterioration of renal function determines the prognosis of ADPKD, depending on
Víctor Martínez
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