Results 111 to 120 of about 21,454 (214)

TRPP2 and autosomal dominant polycystic kidney disease

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2007
Mutations in TRPP2 (polycystin-2) cause autosomal dominant polycystic kidney disease (ADPKD), a common genetic disorder characterized by progressive development of fluid-filled cysts in the kidney and other organs. TRPP2 is a Ca(2+)-permeable nonselective cation channel that displays an amazing functional versatility at the cellular level.
openaire   +2 more sources

End-stage renal disease in autosomal dominant polycystic kidney disease: a comparison of dialysis-related utilization and costs with other chronic kidney diseases

, 2015
Steven M Brunelli,1 Christopher M Blanchette,2,3 Ami J Claxton,1 Debosree Roy,2 Sandro Rossetti,3 Benjamin Gutierrez31DaVita Clinical Research, Minneapolis, MN, USA; 2University of North Carolina, Charlotte, NC, USA; 3Otsuka America Pharmaceutical, Inc.,
Claxton AJ, Blanchette CM, Roy D, Brunelli SM, Gutierrez B, Rossetti S   +5 more
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Echocardiographic characteristics of autosomal dominant polycystic kidney disease

Scientific Reports
Cardiovascular complications in patients with autosomal dominant polycystic kidney disease (ADPKD) are frequently investigated extrarenal manifestations with contradictory outcomes.
Agata Koska-Ścigała, Hanna Jankowska, Magdalena Jankowska, Maria Dudziak, Marcin Hellmann, Alicja Dębska-Ślizień   +5 more
doaj   +1 more source

Immune microenvironment in autosomal dominant polycystic kidney disease

Genes and Diseases
Autosomal dominant polycystic kidney disease (ADPKD) is a common hereditary renal disorder characterized by the progressive development of fluid-filled cysts within the kidneys, leading to renal dysfunction and potentially life-threatening complications.
Cheng Xue, Xinming Li, Chenchen Zhou, Changlin Mei, Zhiguo Mao   +4 more
doaj   +1 more source

Progress on Autosomal Dominant Polycystic Kidney Disease

, 2010
Introduction: Autosomal dominant polycystic kidney disease (ADPKD) is the most common life threatening hereditary disease of the kidney. It is a systemic disease characterized by multiple, bilateral renal cysts that result in massive renal enlargement ...
Schrier, R, A Masoumi, Elhassan, E, E Elhassan, R Schrier, Masoumi, A   +5 more
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Polycystic kidney disease: inheritance, pathophysiology, prognosis, and treatment

, 2010
Christian R Halvorson1, Matthew S Bremmer1, Stephen C Jacobs11Department of Surgery, University of Maryland School of Medicine, Baltimore, MD, USAAbstract: Both autosomal dominant and recessive polycystic kidney disease are conditions with severe ...
Stephen C Jacobs, Matthew S Bremmer, Christian R Halvorson   +2 more
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Targeting TRPM3 As a Potential Therapeutic Approach for Autosomal Dominant Polycystic Kidney Disease

Cystic diseases, especially autosomal dominant polycystic kidney disease (ADPKD; incidence approx. 1/1000), are a leading cause of renal failure, caused by appearance and growth of renal cysts that can lead to renal failure in middle age.
Gul, Huseyin
core   +1 more source

Autosomal dominant polycystic kidney disease

, 2018
Autosomal dominant polycystic kidney disease (ADPKD) is a diagnosis typically made following imaging of the renal tract. The characteristic features of enlarged bilateral polycystic kidneys with or without liver cysts and a positive family history allow ...
Richard Sandford
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Autosomal dominant polycystic kidney disease [PDF]

Journal of Medical Genetics, 1996
openaire   +1 more source

Renal Manifestations of Autosomal Dominant Polycystic Kidney Disease

Turkish Journal of Nephrology, 2019
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Ali Rıza ODABAŞ
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