Results 61 to 70 of about 105,912 (274)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Between-Word Assimilation and Syntax in Child Language Development: a Case Study [PDF]

open access: yes, 2012
Previous developmental research has shown that interactions exist between the emergence of connected speech processes and the acquisition of syntax. This study is the first to have investigated these interactions in detail, using a dense data corpus ...
Bryan, Sarah Catherine
core  

Miejsce epigrafiki i heraldyki w polskim dziedzictwie historycznym na wschodnich ziemiach dawnej Rzeczypospolitej i prace Zakładu Nauk Pomocniczych Historii Uniwersytetu Jagiellońskiego nad jego ocaleniem

open access: yesPrace Historyczne
Between 1994 and 2008, a team composed of students from the Epigraphy Section of the Student Historical Society at the Jagiellonian University, doctoral candidates, and young scholars, led by Wojciech
Wojciech Drelicharz
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

THE PLACE AND ROLE OF ARCHEOLOGY, ETHNOGRAPHY, SOURCE STUDIES AND HISTORIOGRAPHY IN THE COVERAGE OF WORLD HISTORY

open access: yes, 2023
<p>The article describes how important the role of special historical disciplines is in highlighting the facts and hypotheses of world history. Archeology, ethnography, source studies and historiography are auxiliary historical sciences that are ...
Ozodbekova, G.A.
core   +1 more source

Auf Messers Klinge – Materielle Kultur im Spiegel illuminierter Urkunden. Ein Forschungsprojekt im virtuellen Raum

open access: yesMemo, 2018
Illuminierte Urkunden erfordern als Objekte mit Text-Bild-Kombinationen einen interdisziplinären Zugang, um sie angemessen zu erforschen. Expertinnen und Experten im Feld der Kunstgeschichte, der Historischen Hilfswissenschaften – allen voran der ...
Markus Gneiß, Andreas Zajic
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Tadija Smičiklas, Lecturer in Historical Auxiliary Sciences at the Faculty of Arts of Zagreb University

open access: yes, 2000
Na temelju neobjavljene građe iz fonda Zapisnici Mudroslovnog fakulteta i Spisi Mudroslovnog fakulteta Arhiva Filozofskog fakulteta Sveučilišta u Zagrebu autor donosi dosad nepoznate podatke o Tadiji Smičiklasu kao profesoru PPZ na Filozofskom fakultetu ...
Jurković, Ivan, Ivan Jurković
core  

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