Results 81 to 90 of about 105,912 (274)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Pozůstalost archiváře Theodora Rosenthala
Studia Historica Brunensia, 2015 Author presents basic overview of the papers of the archivist and historian Theodor Anton Taulow von Rosenthal (1702–1779), founder and the first archivist of Home, Court and State Archives (Haus-, Hof- und Staatsarchiv) in Vienna. Rosenthal created many
Jan Kahuda
doaj
Историко-географический журналThe publication includes the letters by O. M. Medushevskaya to V. K. Yatsunskiy written in 1956–1966. They are of interest to the study of the beginning of O. М. Medushevskaya’s research path, which is associated with historical geography and the history
T. K. Kholmatov
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
, 1910 The sources of Church history, Sciences auxiliary to Church history and The literature of Church history: v.1, p.
Dessoulavy, C. L. (Charles Louis) +1 more
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Auxiliary Sciences of History: Yesterday, Today and Tomorrow
, 2020 U članku se propituju uloga i značenje Pomoćnih povijesnih znanosti (PPZ) u hrvatskoj historiografiji u sadašnjem trenutku s osvrtom na ulogu koju su imale u razvoju hrvatske povijesne znanosti. U trenucima postmoderne specifična znanja se guraju u drugi
Matijević Sokol, Mirjana
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Prace HistoryczneThis article explores the exceptionally rich collection of photographs of medieval documents housed in the Department of Auxiliary Sciences of History and Source Studies at the Institute of History ...
Andrzej Marzec, Marcin Starzyński
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
A comprehensive study of floods in Poland in the 17th–18th centuries
Journal of Hydrology: Regional StudiesStudy region: Poland, with the regions of Baltic Coast and Pomerania, Masuria-Podlasie, Greater Poland, Masovia, Silesia, and Lesser Poland located in the basins of the Baltic Coast rivers, the Vistula River and the Oder River.
Babak Ghazi +5 more
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