Results 91 to 100 of about 170,805,909 (263)

Counterfactuals and the loss of BE in the history of English [PDF]

open access: yes, 2008
In the course of the ME period, HAVE began to encroach on territory previously held by BE. According to Rydén and Brorström (1987); Kytö (1997), this occurred especially in iterative and durational contexts, in the perfect infinitive and modal ...
McFadden, Thomas, Alexiadou, Artemis
core  

Birmingham Botanical Society Auxiliary 1991 - 1993

open access: yes, 1991
This document is a scrapbook created by the Birmingham Botanical Gardens ...
Birmingham Botanical Society Auxiliary
core   +1 more source

Genealogy in the System of Modern Knowledge: Theory and Methodology of Cognitive History of O.M. Medushevskaya

open access: yesRUDN Journal of Russian History
The author analyzes the place of genealogy as a unique indicator of humanitarian culture both in historical retrospect and modern society, since the subject of its study has traditionally been universal human values - family, kinship and relationships ...
Irina V. Sabennikova
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Auxiliary cook book

open access: yes, 1909
This cookbook is a part of the Shelf2Life Cooking and Recipes Collection, a unique set of pre-1923 cookbooks and other materials focused on food preparation, preservation and cooking instruction providing cooking and baking enthusiasts a one-of-a-kind ...
Hebrew Sheltering Guardian Society. Auxiliary Society
core  

A comprehensive study of floods in Poland in the 17th–18th centuries

open access: yesJournal of Hydrology: Regional Studies
Study region: Poland, with the regions of Baltic Coast and Pomerania, Masuria-Podlasie, Greater Poland, Masovia, Silesia, and Lesser Poland located in the basins of the Baltic Coast rivers, the Vistula River and the Oder River.
Babak Ghazi   +5 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Toledo Calling

open access: yes, 2016
Toledo Calling was a bulletin published by B'Nai Women's Auxiliary Number 398. This monthly bulletin provided Toledo area happenings to Jewish men and women serving in the armed forces.
B'Nai Women's Auxiliary Number 398
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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