Results 91 to 100 of about 77,415 (294)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Auxiliary Domain Selection in Cross-Domain Collaborative Filtering
, 2015 The problem of data sparsity largely limits the accuracy of recommender systems in collaborative filtering model. To alleviate the problem, cross-domain collaborative filtering was proposed by harnessing the information from the auxiliary domains ...
Yi, Chang +2 more
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Hydrogen-Enabled Power Systems: Technologies’ Options Overview and Effect on the Balance of Plant
HydrogenHydrogen-based Power Systems (H2PSs) are gaining accelerating momentum globally to reduce energy costs and dependency on fossil fuels. A H2PS typically comprises three main parts: hydrogen production, storage, and power generation, called packages.
Furat Dawood, GM Shafiullah, Martin Anda
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Shiyou jixieAn auxiliary measurement system of nuclear magnetic resonance(NMR)logging tool based on universal acquisition platform was designed to enable the new generation of NMR logging tool to efficiently and accurately acquire information about auxiliary ...
Zhong Jian +5 more
doaj
A Constrained Multi-Objective Optimization Algorithm with a Population State Discrimination Model
MathematicsThe solution to constrained multi-objective optimization problems (CMOPs) requires optimizing the objective functions while satisfying the constraint conditions. To effectively address CMOPs, algorithms must balance objectives and constraints.
Shaoyu Zhao +3 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
, 2014 The short-circuit current of a Low-Voltage (LV) auxiliary power system of the fossil fuel power plant influences the selection of the LV switch directly.
He HY(何宏源) +2 more
core
Generating Selected Color using RGB, Auxiliary Lights, and Simplex Search
MATEC Web of Conferences, 2015 A mixed light source generates various colors, with the potential to adjust intensities of multiple LEDs, which makes it possible to generate arbitrary colors.
Kim HyungTae +4 more
doaj +1 more source