Results 111 to 120 of about 77,415 (294)

Auxiliary selection in Italian and French. A comparative study of the so-called peripheral verbs. [PDF]

This thesis investigates the intricate phenomenon of auxiliary selection in two Romance languages, namely Italian and French. The primary objective is to elucidate the factors that influence the choice between the auxiliaries ‘be’ and ‘have’ in the ...
Viale, Greta.
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Prior elicitation and variable selection for bayesian quantile regression [PDF]

, 2013
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Bayesian subset selection suffers from three important difficulties: assigning priors over model space, assigning priors to all components of the regression
Al-Hamzawi, Rahim Jabbar Thaher
core  

Permanent Magnet Installation Optimization of Outer Rotor PMSM Depending on Adding Auxiliary Teeth

World Electric Vehicle Journal
To reduce the influence of the permanent magnet (PM) installation error on the electromagnetic characteristics of the outer rotor permanent magnet synchronous motor (OPMSM), the rotor structure of the OPMSM is optimized in this paper.
Jiayin Su, Rui Nie, Peixin Wang, Shuai Xu, Jing Liang, Jikai Si   +5 more
doaj   +1 more source

Auxiliary selection and participial agreement

, 2016
Abstract The main goal of this chapter is to critically address from a comparative perspective some of the most important issues regarding the syntax of Romance auxiliary selection and past participle agreement, covering such areas as auxiliary splits licensed by verb class, person, tense, and mood; triple auxiliation; behaviour of ...
openaire   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

The perfect auxiliary selection of German : a lexicalistic account without unaccusativity

, 2015
Diese Arbeit beschäftigt sich mit der Frage, nach welchen Prinzipien die Verben des Deutschen ihr Perfekt mit "haben" oder "sein" bilden. Im Wesentlichen werden folgende Antworten auf diese Frage gegeben: (1) In der Tat selegieren nicht die Partizipien (
Strobel, Sven
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Auxiliary instrument of portfolio project selection in Public Institutes.

, 2013
Métodos tradicionais de seleção de portfólio de projetos tendem a privilegiar dimensões e aspectos mais relacionados ao lucro e/ou crescimento. Além dessas dimensões e aspectos, Institutos Públicos podem se orientar por aspectos de dimensões que, a ...
Léo Teobaldo Kroth, Kroth, Léo Teobaldo   +1 more
core   +1 more source