Results 131 to 140 of about 77,415 (294)
Auxiliary selection in present-day Italian
, 2020 This thesis is dedicated to researching the use and importance of auxiliary verbs in tempi composti (compound tenses) in Italian language and grammar.
SIROVÁ, Lucie
core
, 2022 reservedL’elaborato affronta la tematica della selezione degli ausiliari in lingue romanze e germaniche. In particolare, lo scopo è quello di ripercorrere l’evoluzione da inglese antico-medio a moderno e operare un confronto con le principali lingue ...
SEMENZATO, MARTINA
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Design process and equipment selection for auxiliary ventilation system [PDF]
, 2000 The design of auxiliary ventilation system (AVS) and optimal equpment selection can be a problem, especially in case of very long drivages and high rock temperature.Algorithms for calculation of AVS parameters are basically developed by use of essential ...
Krstev, Boris, Mirakovski, Dejan
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Our study focuses on the longitudinal acquisition of Italian as an L2 by a group of immigrant children having different languages as hereditary languages (Wu, Hurdu, Arabic, Polish, Romanian, Yoruba, Tagalog, Wolof).
Giuliano Patrizia, Cennamo Michela
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Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Between-Word Assimilation and Syntax in Child Language Development: a Case Study [PDF]
, 2012 Previous developmental research has shown that interactions exist between the emergence of connected speech processes and the acquisition of syntax. This study is the first to have investigated these interactions in detail, using a dense data corpus ...
Bryan, Sarah Catherine
core
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source