Results 111 to 120 of about 1,148,476 (289)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

PENGARUH OVERCONFIDENCE, REPRESENTATIVENESS, AVAILABILITY, DAN ANCHORING BIAS TERHADAP PENGAMBILAN KEPUTUSAN INVESTASI DI KOTA BENGKULU

open access: yes, 2020
Investor sering membuat keputusan investasi secara tidak rasional. Keputusan sering didasarkan pada penilaian mereka yang jauh dari asumsi rasional.
Ridwan, Nurazi, Immanuel, Kristiyan
core  

Behavioral Finance Factors Influence on Investment Decision Making of Individual Investors in PSX and PMEX

open access: yesJournal of Accounting and Finance in Emerging Economies
Purpose: This paper explored how investors in PSX and PMEX make investment decisions that either contribute to the success of PSX and PMEX or seem irrational to them because of the same behavioral factors.
Azam Anwar Khan, Muhammad Waqas
doaj   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Judging Availability Heuristic and Bias within Groups

open access: yes, 2023
The availability heuristic occurs when we make judgements based on our previous knowledge and experiences. Within this, bias could be present, in that the information that is easy to recall has an outsized effect on our judgments.
Oakley, Eliza
core  

The effects of investor personality and perceptual bias in Tehran stock exchange [PDF]

open access: yesتحقیقات مالی, 2010
One of the important factors in making financial decisions is perceptual biases. They influence decisions at the time of exchanging stocks. The present research means to identify these common biases among investors and show its relation with their ...
Rasol Sadi   +2 more
doaj  

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

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