Results 91 to 100 of about 3,187,849 (253)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Assessing the effect of a partly unobserved, exogenous, binary time-dependent covariate on survival probabilities using generalised pseudo-values

BMC Medical Research Methodology, 2018
Background Investigating the impact of a time-dependent intervention on the probability of long-term survival is statistically challenging. A typical example is stem-cell transplantation performed after successful donor identification from registered ...
Ulrike Pötschger, Harald Heinzl, Maria Grazia Valsecchi, Martina Mittlböck   +3 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Specific Disease Knowledge as Predictor of Susceptibility to Availability Bias in Diagnostic Reasoning: a Randomized Controlled Experiment. [PDF]

J Gen Intern Med, 2021
Mamede S, Goeijenbier M, Schuit SCE, de Carvalho Filho MA, Staal J, Zwaan L, Schmidt HG.   +6 more
europepmc   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Behavioral Finance Factors Influence on Investment Decision Making of Individual Investors in PSX and PMEX

Journal of Accounting and Finance in Emerging Economies
Purpose: This paper explored how investors in PSX and PMEX make investment decisions that either contribute to the success of PSX and PMEX or seem irrational to them because of the same behavioral factors.
Azam Anwar Khan, Muhammad Waqas
doaj   +1 more source

The effects of investor personality and perceptual bias in Tehran stock exchange [PDF]

تحقیقات مالی, 2010
One of the important factors in making financial decisions is perceptual biases. They influence decisions at the time of exchanging stocks. The present research means to identify these common biases among investors and show its relation with their ...
Rasol Sadi, Aryan Gholipour, Fattaneh Gholipour   +2 more
doaj  

Availability Bias Dalam Pengambilan Keputusan Kredit

, 2017
Tujuan penelitian ini untuk mengetahui apakah terdapat kecenderungan availability bias dalam pengambilan keputusan kredit pada pengusaha UMKM industri konveksi di Kecamatan Tingkir, Salatiga.
Ristiana, Ana
core  

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Home bias in officiating: Evidence from international cricket

, 2014
We use data on leg before wicket decisions from 1000 test cricket matches to quantify the systematic bias by officials (umpires) to favour home teams. We exploit recent changes in the regulation of test cricket as a series of natural experiments to help ...
Gregory-Smith, I., Gregory-Smith, Ian, Abhinav Sacheti, Sacheti, A., Paton, David, Ian Gregory-Smith, Sacheti, Abhinav, Patón, D., David Paton   +8 more
core   +1 more source