Results 141 to 150 of about 2,200,787 (324)
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Effects of pollen availability and the mutation bias on the fixation of mutations disabling the male specificity of self‐incompatibility [PDF]
Takashi Tsuchimatsu, Kentaro K. Shimizu
openalex +1 more source
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
The Availability Trap: How the Availability Bias and Fitness Influencers Mould Followers’ Behaviour
The advent of social media has opened up a gateway of opportunities to provide people with information and means to a healthier lifestyle. However, due to this, there has also been a change in what people consider to be “normal”. With social media apps like Instagram and TikTok, people fall prey to the “Availability Bias” in which individuals rely on ...
Ammar Lokhandwala - +2 more
openaire +1 more source
Selection bias when using instrumental variable methods to compare two treatments but more than two treatments are available [PDF]
Ashkan Ertefaie +3 more
openalex +1 more source
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Revealed Preferences, Choices, and Psychological Indexes [PDF]
This paper develops a model of choice that embeds some psychological aspects affecting decision maker's behaviour. In the model, the decision maker attaches an unobservable psychological index -representing, e.g., the level of perceived availability or ...
Ivan Soraperra
core
Evaluating food availability and nest predation risk as sources of bias in aural bird surveys [PDF]
Bruce A. Robertson +2 more
openalex +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source

