Results 91 to 100 of about 12,712 (262)

Continuous Purification of mRNA Produced by In Vitro Transcription Using High Performance Countercurrent Membrane Purification

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Messenger ribonucleic acid (mRNA) therapeutics produced by in vitro transcription must be purified to remove residual enzymes and free nucleotides. This study examines the use of high‐performance countercurrent membrane purification (HPCMP) for the purification of mRNA therapeutics based on differences in the rate of diffusion across ...
Ziqiao Wang   +3 more
wiley   +1 more source

INFLUENCE OF ANODIC ALUMINA USED AS SEPARATING DIELECTRIC OF SILICON AVALANCHE LEDs ON DIODE CHARACTERISTICS

open access: yesДоклады Белорусского государственного университета информатики и радиоэлектроники, 2019
A study of the influence of the formation regimes of avalanche LEDs based on nanostructured silicon on the parameters of the formed devices, such as the light emission voltage and the stability of operation has been performed.
Vi Le Dinh   +4 more
doaj   +1 more source

Enhanced strategies for cuproptosis‐like death in bacterial infection treatment

open access: yesBMEMat, EarlyView.
This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang   +7 more
wiley   +1 more source

A Systemic Model for Understanding Business Interactions With Biodiversity and Ecosystems

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Biodiversity loss and ecosystem degradation represent critical threats to human well‐being and economic resilience, challenging businesses to understand and manage their interdependence with natural systems. This study develops a systemic framework—the BioModel—that elucidates the reciprocal relationship between businesses, biodiversity, and ...
Lino Cinquini   +2 more
wiley   +1 more source

Viscosity of concentrated mRNA solutions: Implications for downstream processing

open access: yesBiotechnology Progress, EarlyView.
Abstract Messenger RNA (mRNA) therapeutics can be used to protect against infectious disease and for the treatment of cancers and genetic disorders. In order to obtain the desired therapeutic dosage, it is necessary to concentrate the mRNA to levels where the viscosity of the mRNA solutions can become significant.
Amin Javidanbardan   +3 more
wiley   +1 more source

Force oscillations distort avalanche shapes

open access: yesMaterials Research Letters, 2019
Contradictory scaling behavior in experiments testing the principle of universality may be due to external oscillations. Thus, the effect of damped oscillatory external forces on slip avalanches in slowly deformed solids is simulated using a mean-field ...
Louis W. McFaul   +3 more
doaj   +1 more source

Dynamic Calibration of DEM Simulations Using Rotating Drum Experiments Using the Mean Absolute Error

open access: yesChemie Ingenieur Technik, EarlyView.
Calibrating DEM simulations is challenging due to unknown microscopic parameters. Rotating drum experiments are combined with image‐based analysis and Latin Hypercube Sampling (LHS). An area‐based Mean Absolute Error (MAE) enables reliable identification of optimal parameter sets.
Marius Hoffmann   +2 more
wiley   +1 more source

Ag‐Induced Phase and Defect Engineering of Co‐Evaporated Sb2Se3 Thin Films for Enhanced Photovoltaic Performance

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
The sequential formation of Ag2Se and AgSbSe2 phases at the Sb2Se3/Mo interface upon Ag incorporation in co‐evaporated Sb2Se3 solar cells promotes grain growth and defect passivation. These newly formed intermediate phases enhance crystallinity and suppress recombination, leading to significant improvements in open‐circuit voltage, fill factor, and ...
Van‐Quy Hoang   +16 more
wiley   +1 more source

Advancing super‐resolution stimulated emission depletion microscopy with luminescent lanthanide nanocrystals

open access: yesFlexMat, EarlyView.
The state‐of‐the‐art research advances and its cutting‐edge application in super resolution stimulated emission depletion technology based on luminescent lanthanide nanocrystals. Abstract Stimulated emission depletion (STED) microscopy overcomes the diffraction limit to reveal subcellular structures beyond the reach of conventional optical methods ...
Yaqi Chen   +4 more
wiley   +1 more source

Effect of Electromyography Findings of Traction‐Related Signal Loss on Prognosis During Neuromonitored Thyroidectomy

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Intraoperative neuromonitoring (IONM) is a reliable tool to detect electromyographic loss of signal (LOS). Here, we investigated the effect of electromyography features of traction‐related LOS on prognosis. Methods Thyroidectomy patients with a traction‐related LOS were included.
Serkan Karaisli   +3 more
wiley   +1 more source

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