Results 101 to 110 of about 346 (137)

Avarone and Avarol

Drugs of the Future, 1985
W.E.G. Mueller, R.K. Zahn, A. Maidhof, E. Eich, M.J. Gasic, H.C. Schroeder   +5 more
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ChemInform Abstract: Stereoselective Synthesis of (+)‐Avarol, (+)‐Avarone, and Some Nonracemic Analogues.

ChemInform, 1997
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Ji Eun An, David F. Wiemer
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Avarol-induced DNA strand breakage in vitro and in Friend erythroleukemia cells.

Cancer research, 1987
The hydroquinone-containing cytostatic compound avarol inhibits predominantly growth of those cell lines which have a low level of superoxide dismutase. The substrate of this enzyme, the superoxide anion, was found to be formed during the in vitro oxidation reaction of avarol to its semiquinone radical in the presence of oxygen.
Wernér E.G. Müller, Dušan Sladić, Rudolf K. Ζahn, K H Bässler, Nikola Dogović, H Gerner, Miroslav J. Gašić, Heinz C. Schröder   +7 more
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Biological Activities of Avarol Derivatives, 1. Amino Derivatives

Journal of Natural Products, 1990
Nine amino derivatives, compounds 3-11. of avarone were synthesized. Their antibacterial and cytotoxic activities are evaluated, and the results of a prescreen for antitumor effects are reported.
Cozzolino, R., De Giulio, A., De Rosa, S., Strazzuixllo, G., Gašić, M.J., Sladić, Dušan, Zlatović, Mario   +6 more
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Enantioselective Total Synthesis of Avarol and Avarone

Angewandte Chemie International Edition, 1999
Formation of the C11-C1' bond through application of Barton's radical decarboxylation and quinone addition is the cornerstone of a new convergent and concise synthesis of the marine metabolites avarol (1) and avarone (2; see scheme), for which antimitotic, antileukemic, and antiviral effects have been reported.
, Ling, , Xiang, , Theodorakis
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Avarol, a sesquiterpenoid hydroquinone from Dysidea avara

Acta Crystallographica Section C Crystal Structure Communications, 1994
The X-ray analysis of avarol, 2-[(1,2,3,4,4a,7,8,8a-octahydro-1,2,4a,5-tetramethyl-1-naphthalenyl)methyl]-1,4-benzenediol, C 21 H 30 O 2 , confirms the stereochemistry previously given on the basis of spectral measurements (De Rosa, Minale, Riccio & Sodano, 1976).
R. Puliti, S. De Rosa, MATTIA, Carlo
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Antibacterial and Antifungal Activity of Avarone and Avarol

Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology, 1985
The sesquiterpenoid hydroquinone and quinone, Avarol and Avarone, were previously found to be potent antitumor agents (Müller et al., 1984). In the present study it is reported that in aqueous solution (pH 7.2), in the presence of dimethylsulfoxide, Avarol is converted to Avarone.
G, Seibert, W, Raether, N, Dogović, M J, Gasić, R K, Zahn, W E, Müller   +5 more
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Synthesis and Biological Activities of Thio-avarol Derivatives

Journal of Natural Products, 2008
Eleven new thio-avarol derivatives (3-13) were synthesized. Their antimicrobial, brine shrimp lethality, and free-radical scavenging activities and acetylcholinesterase inhibition, together with 12 already reported semisynthetic thio-avarol derivatives (14-25), were evaluated.
Boris Pejin, Carmine Iodice, Giuseppina Tommonaro, Salvatore De Rosa   +3 more
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Further bioactive derivative of avarol from Dysidea avara

Tetrahedron, 1990
Abstract A new bioactive derivative of avarol, 6'-hydroxy,5'-acetyl-avarol ( 3 ), has been isolated from the marine sponge Dysidea avara and characterized mainly by spectral analysis. Its biological activities are also reported. The occurrence of diacetyl-avarol ( 1b ) as natural metabolite is reported.
A De Giulio, S De Rosa, G Di Vincenzo, G Strazzullo   +3 more
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Crystal Studies of Avarol Derivatives. 5'-Acetylavarol from Dysidea avara

Acta Crystallographica Section C Crystal Structure Communications, 1995
The X-ray analysis of the natural product 5'-acetylavarol {4-hydroxy-3-[(1,2,3,4,4a,7,8,8a-octahydro-1,2,4a,5-tetramethyl-1-naphthyl)methyl]phenyl acetate, C 23 H 32 O 3 } confirms the previous structure elucidation of Crispino, De Giulio, De Rosa & Stazzullo [J. Nat. Prod. (1989), 52, 646-648], which was made on the basis of chemical and spectral data.
R. Puliti, S. De Rosa, MATTIA, Carlo
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