Results 111 to 120 of about 30,097 (277)

Modeling the hallmarks of avascular tumors [PDF]

open access: yesarXiv
We present a stochastic computational model of avascular tumors, emphasizing the detailed implementation of the first four so-called hallmarks of cancer: self-sufficiency in growth factors, resistance to growth inhibitors, avoidance of apoptosis, and unlimited growth potential.
arxiv  

A Patient Centric Model for Vaso‐Occlusive Crises in Sickle Cell Disease—Outcomes of a Consensus Exercise Conducted Across Patients and Experts

open access: yesClinical and Translational Science, Volume 18, Issue 4, April 2025.
ABSTRACT Sickle cell disease (SCD) is a group of inherited disorders caused by a mutation in the beta globin gene that leads to sickling of red blood cells and results in anemia and Vaso‐occlusive crises (VOC). VOC are described as an acute worsening of symptoms impacting daily life and often requiring treatment to resolve.
Pooja Nandi   +2 more
wiley   +1 more source

Treatment of Femoral Neck Fractures in Adults With Improved Biplane Double‐Supported Screw Fixation and Femoral Neck System: Complications and Surgical Techniques

open access: yesOrthopaedic Surgery, Volume 17, Issue 4, Page 1057-1066, April 2025.
The newly designed guide in this study facilitates the insertion of the lower BDSF screw and shortens the learning curve. There was no significant difference in the overall postoperative complication rates between the BDSF and FNS groups. Although BDSF has drawbacks, including a longer learning curve and a potential risk of subtrochanteric fractures ...
Xiaolong Zhang   +10 more
wiley   +1 more source

A Topological Data Analysis Framework for Quantifying Necrosis in Glioblastomas [PDF]

open access: yesarXiv
In this paper, we introduce a shape descriptor that we call "interior function". This is a Topological Data Analysis (TDA) based descriptor that refines previous descriptors for image analysis. Using this concept, we define subcomplex lacunarity, a new index that quantifies geometric characteristics of necrosis in tumors such as conglomeration ...
arxiv  

Core decompression in avascular necrosis of the hip in sickle‐cell disease [PDF]

open access: bronze, 1996
Lori Styles, Elliott Vichinsky
openalex   +1 more source

The Role of Exerkines in the Treatment of Knee Osteoarthritis: From Mechanisms to Exercise Strategies

open access: yesOrthopaedic Surgery, Volume 17, Issue 4, Page 1021-1035, April 2025.
Exercise‐induced exerkines like interleukin‐6, insulin‐like growth factor‐1, and transforming growth factor‐β offer targeted benefits in knee osteoarthritis therapy, reducing inflammation, promoting cartilage repair, and relieving pain. This study highlights personalized exercise as a promising, noninvasive strategy to harness these molecular effects ...
Yuxiong Xu   +7 more
wiley   +1 more source

Treatment of traumatic disruption of the suspensory apparatus in Thoroughbred racehorses at risk of proximal interphalangeal joint subluxation using a locking compression‐distal femur plate for double arthrodesis

open access: yesVeterinary Surgery, Volume 54, Issue 3, Page 439-452, April 2025.
Abstract Objective To describe the outcome of metacarpophalangeal (MCPJ) and proximal interphalangeal joint (PIPJ) arthrodesis using a locking compression‐distal femur plate (LCP‐DFP) in Thoroughbred racehorses with traumatic disruption of the suspensory apparatus (TDSA) at risk of PIPJ subluxation.
David Orozco Lopez   +5 more
wiley   +1 more source

Partial Humeral Head Resurfacing for Avascular Necrosis

open access: yesArthroscopy Techniques, 2020
Large chondral lesions of the humeral head are often treated with total shoulder arthroplasty, but this may not be an ideal option for young, active patients.
Elise C. Bixby, M.D.   +4 more
doaj  

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