Results 141 to 150 of about 254,014 (176)

Lost in Translation: Why Biologic Therapies for Intervertebral Disc Degeneration and Low Back Pain Have Not Reached the Clinic (Yet)

JOR SPINE, Volume 9, Issue 3, September 2026.
From preclinical promise to clinical translation in intervertebral disc degeneration (IDD). Robust preclinical evidence supports a range of biologic therapies, with consistent improvements in imaging, extracellular matrix composition, inflammation, and behavior.
Luca Ambrosio, Jordy Schol, Clara Ruiz‐Fernandez, Vincenzo Denaro, Gianluca Vadalà, Daisuke Sakai   +5 more
wiley   +1 more source

Bilateral Panners disease in sickle cell anaemia: Case report

The Annals of African Surgery, 2008
Avascular necrosis is common in sickle cell disease in various vulnerable areas such as in the femoral or humeral heads. Panner’s disease however is described as avascular necrosis of the capitellum, which commonly occurs in a younger age group.
T.W. King
doaj  

Biocompatibility Assessment of Lithium‐Ion Battery Materials in Medical Devices

Small Structures, Volume 7, Issue 9, September 2026.
How safe are lithium‐ion battery materials for medical devices? Antimicrobial performance, cytotoxicity, and biotoxicity are systematically evaluated, and a multidimensional risk‐assessment framework is developed to classify materials from negligible to high risk.
Tingyu Hua, Ming Xu, Zhuofei Jia, Zhiwei Tao, He Yin, Jinzhi Lv, Shanshan Li, Jianan Wang, Wei Yan, Jinhai Wang, Yunlong Zhao   +10 more
wiley   +1 more source

Proliferative Sparganosis Due to Spirometra mansoni in a Dog: A Detailed Diagnostic Picture

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Innumerable small oval cystic structures were identified in the peritoneal cavity of a young dog presenting with abdominal distension and weight gain. A combination of diagnostics confirmed these structures as Spirometra mansoni plerocercoids and established a diagnosis of proliferative sparganosis.
Stephanie Middlemast, Nicholas Lim, Charles G. Gauci, Abdul Jabbar   +3 more
wiley   +1 more source

Beta Thalassemia and Chronic Myeloid Leukemia: Dual Diagnosis Under the Microscope

International Journal of Laboratory Hematology, Volume 48, Issue 5, Page 931-933, October 2026.
Paige Muir, Mohammad Bahmanyar, Hamish Nicolson, Hayley Merkeley   +3 more
wiley   +1 more source

Aniridia‐associated keratopathy: Clinical and molecular mechanisms of disease progression and emerging therapeutic targets

Acta Ophthalmologica, Volume 104, Issue 6, Page 604-615, September 2026.
Abstract Congenital aniridia is a rare genetic disorder primarily caused by pathogenic variants of the PAX6 gene. It leads to various panocular anomalies, including aniridia‐associated keratopathy (AAK). This review highlights recent insights into its pathogenesis, focusing on clinical staging, microstructural changes in the cornea and molecular ...
N. Szentmáry, S. Suiwal, M. Amini, F. N. Fries, A. Náray, L. Latta, Z. Li, S. Li, S. Liu, S. L. Hsu, S. Kundu, G. Tóth, S. Trusen, J. Zimmermann, B. Seitz, B. Käsmann‐Kellner, Z. Hoxha, A. Langenbucher, O. Stachs, M. Cortón‐Perez, K. Tory, A. Csorba, Z. Z. Nagy, M. C. Acosta, J. Gallar, M. Csidey, E. Maka, T. Stachon   +27 more
wiley   +1 more source

Hydroxyurea (hydroxycarbamide) use in adults with haemoglobin SC disease: A real‐world study in Quebec

British Journal of Haematology, Volume 209, Issue 3, Page 1291-1300, September 2026.
Summary Haemoglobin SC (HbSC) disease is the second most prevalent form of sickle cell disease, but evidence for hydroxyurea (hydroxycarbamide; HU) to prevent pain episodes was limited until the prospective identification of variables as outcomes for treatment (PIVOT) trial.
Alice Girard, Laurianne Charette, Mélissa Haouchine, Laurence Bozec, Mohamed Zakaria Bachir Bouyadjera, Mariane Poitras, Vincent‐Thierry Taillefer, Chloé Trudeau, Yves Pastore, Nathalie Letarte, Stéphanie Forté   +10 more
wiley   +1 more source

Hydroxyurea (hydroxycarbamide) in haemoglobin SC disease: Moving from therapeutic hesitation to evidence‐guided care

British Journal of Haematology, Volume 209, Issue 3, Page 1428-1430, September 2026.
Girard et al. report a retrospective, single‐centre, real‐world study evaluating hydroxyurea (hydroxycarbamide) use in adults with haemoglobin SC disease in Quebec. Hydroxyurea was associated with reduced vaso‐occlusive crisis composite events, mostly mild adverse events and no observed hyperviscosity‐related complications, while highlighting adherence
Tahereh Setayesh
wiley   +1 more source

The Emerging Role of UCHL1 in Neurological and Musculoskeletal Diseases

Immunology &Cell Biology, Volume 104, Issue 8, Page 783-793, September 2026.
UCHL1‐associated pathology. The pathological role of UCHL1 in multisystem diseases, including cancer, neurological, musculoskeletal and cardiovascular disorders. ABSTRACT Ubiquitin C‐terminal hydrolase L1 (UCHL1) is a highly conserved deubiquitinating enzyme that has transitioned from being viewed as a “brain‐specific” protein to a global regulator of ...
Ru Feng, Xiu Zhong, Jianjun Li, Adrian A. Achuthan   +3 more
wiley   +1 more source

Diabetic Foot Ulcer–Associated Versus Other Lower‐Extremity Necrotising Soft‐Tissue Infections: A Retrospective Cohort Study

International Wound Journal, Volume 23, Issue 9, September 2026.
ABSTRACT To compare clinical characteristics, microbiology, treatment burden and outcomes between lower‐extremity necrotising soft tissue infections associated with diabetic foot ulcers (DFU) and lower‐extremity necrotising soft tissue infections not associated with DFU.
Haowu Tang, Wenchao Guo, Jun He, Xinzhu Song, Kai Wang, Xin Zhang, Zhou Jin, Xiaorui Jiang   +7 more
wiley   +1 more source