Results 51 to 60 of about 576,687 (323)

AAPT Diagnostic Criteria for Chronic Sickle Cell Disease Pain [PDF]

open access: yes, 2017
Pain in sickle cell disease (SCD) is associated with increased morbidity, mortality, and high health care costs. Although episodic acute pain is the hallmark of this disorder, there is an increasing awareness that chronic pain is part of the pain ...
Aguilar   +89 more
core   +3 more sources

Mathematical biomedicine and modeling avascular tumor growth [PDF]

open access: yes, 2012
In this chapter we review existing continuum models of avascular tumor growth, explaining howthey are inter related and the biophysical insight that they provide.
Byrne, H. M.
core   +1 more source

Comorbidities in aging patients with sickle cell disease. [PDF]

open access: yes, 2018
Sickle cell disease (SCD) in general and sickle cell anemia in particular is a highly complex disorder both at the molecular and clinical levels. Although the molecular lesion is a single-point mutation, the sickle gene is pleiotropic in nature causing ...
Ballas, Samir K.
core   +2 more sources

Self‐Feeding of Engineered Tissues via Controlled Glucose Release Facilitates Survival and Vascularization of Living Implants

open access: yesAdvanced Functional Materials, EarlyView.
ABSTRACT Engineering living matter has great clinical potential to deliver functional replacement organs. However, clinical translation remains hampered by the current inability to maintain viability of clinically relevant‐sized constructs. During the pre‐vascular phase, implants rely on nutrient diffusion for survival, which is insufficient at ...
Melvin Gurian   +5 more
wiley   +1 more source

Management Options in Avascular Necrosis of Talus

open access: yesIndian Journal of Orthopaedics, 2018
Avascular necrosis (AVN) of the talus can be a cause of significant disability and is a difficult problem to treat. The most common cause is a fracture of the talus. We have done a systematic review of the literature with the following aims: (1) identify
Mandeep Singh Dhillon   +4 more
semanticscholar   +1 more source

Visible Light Induced DLP‐Printed Oxygen‐Releasing TPMS Scaffolds Mitigate Early Hypoxia in Bone Defects

open access: yesAdvanced Healthcare Materials, EarlyView.
Visible light‐induced digital light processing 3D printed Primitive‐triply periodic minimal surface hydrogels embed CaO2–Si core–shell nanoparticles to deliver short‐term oxygen during the avascular window. The scaffolds maintain cytocompatibility, elevate osteopontin in vitro, and enhance calvarial defect repair in vivo without toxicity.
Anastasia B. Timoshenko   +11 more
wiley   +1 more source

Avascular Necrosis of Femoral Head: A Retrospective Study of MRI Scans [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2019
Introduction: Avascular necrosis of the femoral head is commonly encountered now-a-days with increasing use of steroids and alcohol. MRI is considered the most effective diagnostic investigation for avascular necrosis and is helpful for screening and ...
Prateek Singh Gehlot   +3 more
doaj   +1 more source

A systematic review of undisplaced femoral neck fracture treatments for patients over 65 years of age, with a focus on union rates and avascular necrosis

open access: yesJournal of Orthopaedic Surgery and Research, 2017
BackgroundIt remains unclear whether conservative treatment should be used to treat the common undisplaced femoral neck fractures that develop in the elderly.
Danfeng Xu   +4 more
semanticscholar   +1 more source

Progressive Insights into 3D Bioprinting for Corneal Tissue Restoration

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores the potential of 3D bioprinting to replicate the complex structure and function of the human cornea. It highlights key advances in bioink development, printing modalities, and in vivo performance, while addressing current challenges and emerging strategies. The review emphasizes bioprinting's promise to overcome donor shortages and
Ilayda Namli   +6 more
wiley   +1 more source

Hawkins II and III Talus Neck Fractures: Complication Rates and Utility of Hawkins Sign

open access: yesFoot & Ankle Orthopaedics
Category: Trauma; Ankle Introduction/Purpose: Talus neck fractures typically result from hyperdorsiflexion in high-impact accidents like motor vehicle crashes and falls from significant heights.
Logan Lake   +7 more
doaj   +1 more source

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