Results 121 to 130 of about 5,891 (154)

Cyclic Tetraindoles with a Cyclooctatetraene Core: Controlling Planarity and Antiaromatic Character via N-Alkylation. [PDF]

Chemistry
Fujimoto K, Hirose R, Masu H, Takahashi M.   +3 more
europepmc   +1 more source

SIRT1 Activation by Lignans Identified via UPLC-qTOF-MS/MS-Based Metabolomic Profiling of <i>Piper longum</i> L. Fruit (Long Pepper). [PDF]

Plants (Basel)
Mai VH, Yang JL, Ha TK, Ponce-Zea JE, Le MTT, Lee BW, An JP, Oh WK.   +7 more
europepmc   +1 more source

Fatal Non-Hepatic Hyperammonemia Post-Glofitamab: Ureaplasma and Genetic Susceptibility: A Case Report. [PDF]

Immun Inflamm Dis
Wu Y, Guo X, Wang X, Guo F.
europepmc   +1 more source

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Avenanthramide C from Oats Protects Pyroptosis through Dependent ROS-Induced Mitochondrial Damage by PI3K Ubiquitination and Phosphorylation in Pediatric Pneumonia

Journal of Agricultural and Food Chemistry, 2022
Oat containing rich β-glucan, polyphenols, flavonoids, saponins, alkaloids, and other substances shows good biological activities. Therefore, the present study aimed to uncover the possible mechanism and therapeutic effect of Avenanthramide C in lessening inflammatory responses in pediatric pneumonia.
Zhichen Pu
exaly   +3 more sources

Oat Avenanthramide-C (2c) Is Biotransformed by Mice and the Human Microbiota into Bioactive Metabolites [PDF]

Journal of Nutrition, 2015
Avenanthramides (AVAs), which are found exclusively in oats, may play an important role in anti-inflammation and antiatherogenesis. Although the bioavailability of AVAs has been investigated previously, little is known about their metabolism.The aim of the present study was to investigate the metabolism of avenanthramide-C (2c), one of the major AVAs ...
Huadong Chen, Shengmin Sang
exaly   +3 more sources

Avenanthramide-C prevents amyloid formation of bovine serum albumin

Biophysical Chemistry, 2020
The misfolding of protein and its assembly into amyloid fibrils with a characteristic β-sheet-rich secondary structure, cause a lot of illnesses. Polyphenols have been extensively studied as a class of amyloid inhibitors, whose effect depends on the position and number of hydroxyl groups around the flavone backbone.
Maria Guadalupe, Quiroz Vazquez, Dvorak, Montiel Condado, Brenda, Gonzalez Hernandez, Azucena, Gonzalez-Horta   +3 more
openaire   +2 more sources

Avenanthramide-C Activates Nrf2/ARE Pathway and Inhibiting Ferroptosis Pathway to Improve Cognitive Dysfunction in Aging Rats

Neurochemical Research, 2022
Postoperative neurocognitive impairment (POCD) is a common complication after surgery and anesthesia, especially in elderly patients. Avenanthramide-C (AVC) test is a vascular endothelial cell adhesion molecule inhibitor with strong anti-inflammatory and antioxidant effects.
Zijian, Ma, Yang, Ma, Xuefeng, Cao, Yunpeng, Zhang, Tieying, Song   +4 more
openaire   +2 more sources

Yeast cell wall capsules for delivery of oat biomarker avenanthramide-C

Food Chemistry
Avenanthramide-C (AVN-C) is the biomarker for oat with a variety of physiological functions, whereas its application is constrained by low stability and bioavailability. Avenanthramide-C is the biomarker for oat with a variety of physiological functions, whereas its application is constrained by low stability and bioavailability.
Chen Tan
exaly   +3 more sources

Avenanthramide C induces cellular senescence in colorectal cancer cells via suppressing β-catenin-mediated the transcription of miR-183/96/182 cluster

Biochemical Pharmacology, 2022
Cellular senescence is representing a potential anticancer therapeutic arsenal. Avenanthramide C (AVN C), as a signature compound of oats, exhibits antioxidant, anti-inflammatory, anti-atherosclerotic, and anti-tumor activities. However, the relationship between AVN C and cellular senescence in tumors remains largely unclear.
Zhuoyu Li
exaly   +3 more sources

Identification of a novel senomorphic agent, avenanthramide C, via the suppression of the senescence-associated secretory phenotype

Mechanisms of Ageing and Development, 2020
Senescent cells are deeply involved in the induction of tissue damage and aging-related diseases. The identification of factors that eliminate senescent cells or inhibit the senescence-associated secretory phenotype (SASP) in these cells is necessary. Here, we report an avenanthramice C (Avn C) extracted from oat as a new SASP modulator. Treatment with
Jae Sung, Lim, Da Young, Lee, Hyung Seok, Kim, Sang Chul, Park, Joon Tae, Park, Hyeon Sik, Kim, Won Keun, Oh, Kyung A, Cho   +7 more
openaire   +2 more sources