The Adapted POM Analysis of Avenanthramides In Silico [PDF]
Pharmaceuticals, 2023 POM analysis and related approaches are significant tools based on calculating various physico-chemical properties and predicting biological activity, ADME parameters, and toxicity of a molecule.
Michal Jágr +2 more
exaly +6 more sources
The Biosynthetic Pathway of Major Avenanthramides in Oat [PDF]
Metabolites, 2019 Avenanthramides are a group of N-cinnamoylanthranilic acids, with health-promoting properties mainly found in oat (Avena sativa L.). However, the biosynthetic mechanism for the main three types of avenanthramides (Avn-A, Avn-B and Avn-C) is not ...
Zhiyong Li, Yi Chen, Zhiyong Li
exaly +5 more sources
Avenanthramides, Distinctive Hydroxycinnamoyl Conjugates of Oat, Avena sativa L.: An Update on the Biosynthesis, Chemistry, and Bioactivities [PDF]
Plants, 2023 Avenanthramides are a group of N-cinnamoylanthranilic acids (phenolic alkaloid compounds) that are produced in oat plants as phytoalexins, in response to pathogen attack and elicitation.
Chanel J. Pretorius, Ian A. Dubery
doaj +2 more sources
Exploring Nutritional Quality and Bioactive Compounds in Oat Mediterranean Landraces and Cultivars [PDF]
AntioxidantsOat (Avena sativa L.) is increasingly recognized as a functional food due to its unique profile of antioxidant and health-promoting compounds. Beyond its traditional role, our study reveals that Mediterranean landraces and related species harbour ...
Elena Prats +5 more
doaj +2 more sources
Standardization of Germinated Oat Extracts and Their Neuroprotective Effects Against Aβ1-42 Induced Cytotoxicity in SH-SY5Y Cells [PDF]
MoleculesThe present study aimed to standardize germinated oat extracts (GOEs) by profiling avenanthramides (AVNs) and phenolic acids and evaluate their neuroprotective effects against Aβ1-42-induced cytotoxicity in human neuroblastoma (SH-SY5Y) cells.
Yu-Young Lee +6 more
doaj +2 more sources
Food Chemistry: X, 2019 Oats contain a range of phenolic acids and avenanthramides which may have health benefits. Analysis of 22 commercial oat products (oat bran concentrate, oat bran, flaked oats, rolled oats and oatcakes) using HPLC-DAD detected eleven bound and thirteen ...
Peter Shewry +2 more
exaly +3 more sources
Oat-based milk alternatives: the influence of physical and chemical properties on the sensory profile [PDF]
Frontiers in NutritionIntroductionOat-based milk alternatives (OMAs) have become increasingly popular, perhaps due to their low allergenicity and preferred sensory attributes when compared to other milk alternatives. They may also provide health benefits from unique compounds;
Roisin McCarron +4 more
doaj +2 more sources
Avena sativa-derived avenanthramides suppress 12-lipoxygenase activity and downstream arachidonic acid metabolites in letrozole-induced PCOS rats [PDF]
Scientific ReportsPolycystic ovary syndrome (PCOS) implicates hormonal imbalance, ovulation disorders, metabolic disturbances, and chronic low-grade inflammation. In this study, we investigated the inflammation driven by 12-lipoxygenase (12-LOX)-mediated conversion of ...
Yara Walid +3 more
doaj +2 more sources
Quantum chemical investigation of the antiradical property of avenanthramides, oat phenolics
Heliyon, 2021 Avenanthramides (AVs) are polyphenolic components found in oats. The present work is devoted to the exploration of structure-based radical scavenging activity of nine AVs; 2p, 2f, 2c, 1p, 1c, 1f, 1s, 2s, and 3f, using M06-2X functional level of density ...
K Muraleedharan
exaly +3 more sources
Dihydroavenanthramide D Enhances Skin Barrier Function through Upregulation of Epidermal Tight Junction Expression [PDF]
Current Issues in Molecular BiologySkin barrier dysfunction and thin epidermis are hallmarks of sensitive skin and contribute to premature aging. Avenanthramides are the primary bioactive components of colloidal oatmeal, a commonly used treatment to enhance skin barrier function.
Jiye Park +5 more
doaj +2 more sources