Results 71 to 80 of about 911,344 (281)

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Micro-Diversity Analysis of Error Probability and Channel Capacity over Hoyt-Gamma Fading [PDF]

open access: yesRadioengineering, 2017
In wireless communication system, various parameters such as average symbol/bit error probability (ASEP/ABEP), outage probability and average channel capacity, etc. are studied for its performance analysis. In this paper, the performance of L-Hoyt/Gamma (
S. Kumar, S. K. Soni, P. Jain
doaj  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

SVD-based IWFA for next generation wireless MIMO communication

open access: yesICT Express, 2018
Point-to-point MIMO systems without channel state information at the transmitter (No CSIT) and with perfect channel state information at the transmitter (Perfect CSIT) were considered for the application of a novel singular-value-decomposition-based (SVD-
Vinodh Kumar Minchula   +1 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

On the Performance of Optical Wireless Links Over Random Foggy Channels

open access: yesIEEE Access, 2017
Fog and dust are used to be considered as major performance degrading factors for free space optic (FSO) communication links. Despite the number of field measurements, performed in foggy environments during the last decades, most of the proposed channel ...
Maged Abdullah Esmail   +2 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Polar Codes over Fading Channels with Power and Delay Constraints

open access: yes, 2017
The inherent nature of polar codes being channel specific makes it difficult to use them in a setting where the communication channel changes with time.
Deekshith, P. K., Sahasranand, K. R.
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Power Efficiency Evaluation of Mapping Multiplexing Technique and Pulse Amplitude Modulation for Noncoherent Systems

open access: yesIEEE Photonics Journal, 2015
The two-, three-, and four-channel mapping multiplexing technique (MMT) is demonstrated to increase the data capacity of multilevel intensity-modulated transmission formats to 2, 3, and 4 bits/symbol with a substantial reduction in power penalty.
M. A. Elsherif, A. Malekmohammadi
doaj   +1 more source

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