Results 41 to 50 of about 957,315 (213)

Blood Pressure Variability and Adverse Pregnancy and Cardiovascular Outcomes in the ALSPAC Cohort

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Outside pregnancy, blood pressure variability (BPV) predicts cardiovascular events. We aimed to study associations (if any) between visit‐to‐visit BPV in pregnancy and (1) adverse maternal/perinatal outcomes, and (2) long‐term maternal ...
Milly Wilson   +8 more
doaj   +1 more source

P3.02 MORNING BLOOD PRESSURE SURGE, BLOOD PRESSURE VARIABILITY AND AORTIC STIFFNESS IN ESSENTIAL HYPERTENSION

open access: yesArtery Research, 2013
Morning blood pressure surge is associated with increased cardiovascular risk, possibly due to its ability to reflect short-term BP variability and/or its link with arterial stiffness.
G. Pucci   +4 more
doaj   +1 more source

Short-term blood pressure variability as a potential therapeutic target for kidney disease

open access: yesClinical Hypertension, 2023
Short-term blood pressure variability (BPV) measured with ambulatory blood pressure (BP) monitoring has been demonstrated to be significant in predicting various clinical outcomes.
Ye Eun Ko, Jong Hyun Jhee
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

New insights into measurement variability in glaucomatous visual fields from computer modelling.

open access: yesPLoS ONE, 2013
ObjectiveTo develop a model to simulate visual fields (VFs) in glaucoma patients, and to characterize variability of the Mean Deviation (MD) VF summary measurement using real VFs and simulations.MethodsPointwise VF variability was previously approximated
Richard A Russell   +2 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Reliability of beat-to-beat blood pressure variability in older adults

open access: yesScientific Reports
Blood pressure variability (BPV) is emerging as an important risk factor across numerous disease states, including cerebrovascular and neurodegenerative disease in older adults.
Trevor Lohman   +9 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Association between changes in habitual stepping activity and cognition in older adults

open access: yesScientific Reports
Advancing age is associated with declines in cognitive function. Although physical activity is thought to protect against this decline, it is unclear how a short-term uptake in daily steps or a decline in day-to-day step variability may contribute to ...
Myles W. O’Brien   +10 more
doaj   +1 more source

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