BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Establishment and Optimization of a Dynamic Model for Energy and Protein Requirements in Meat Ducks. [PDF]
Li Z, Liu Q, Peng D.
europepmc +1 more source
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Impact of warmer winters on the flowering display of Tokyo cherry (Cerasus ×yedoensis 'Somei-yoshino') at its southern range. [PDF]
Katsuki T +6 more
europepmc +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Food Security Outlook for Eastern Africa by 2050: Climate Change Impacts and Population-Driven Demand Gaps. [PDF]
Simane B +7 more
europepmc +1 more source
A social-ecological trap theory-informed investigation of dietary patterns in southwestern Madagascar. [PDF]
Kelahan H +14 more
europepmc +1 more source
Randomized controlled trial to compare post operative analgesia between ultrasound guided quadratus lumborum and erector spinae plane block in children undergoing pyeloplasty. [PDF]
Kaur N, Pandey M, Varshney PG, Kundal R.
europepmc +1 more source
Color outside the lines: How does amoral management influence employees' creative unethicality? [PDF]
Ren L, Liu Y, Siyal AW, Zhang X, Pu T.
europepmc +1 more source

