Results 61 to 70 of about 395,566 (267)
The Cusum Median Chart for Known and Estimated Parameters
Revstat Statistical Journal, 2019 The usual CUSUM chart for the mean (CUSUM-X¯) is a chart used to quickly detect small to moderate shifts in a process. In presence of outliers, this chart is known to be more robust than other mean-based alternatives like the Shewhart mean chart but it ...
Philippe Castagliola +2 more
doaj +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
IEEE Access, 2018 This paper proposes a control chart using repetitive sampling for monitoring process capability index having one-sided specification limit using an exact distribution.
Muhammad Aslam
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Integral equation solutions for the average run length for monitoring shifts in the mean of a generalized seasonal ARFIMAX(P, D, Q, r)s process running on a CUSUM control chart. [PDF]
PLoS One, 2022 Areepong Y, Peerajit W.
europepmc +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Attribute Control Chart Using the Repetitive Sampling Under Neutrosophic System
IEEE Access, 2019 In this paper, an attribute control chart using the repetitive sampling under the neutrosophic statistics system is discussed. The necessary measures of the proposed control chart under the neutrosophic statistics system are given.
Muhammad Aslam
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
New extended exponentially weighted moving average control chart for monitoring process mean
HeliyonIn this article, we develop a new control chart based on the Exponentially Weighted Moving Average (EWMA) statistic, termed the New Extended Exponentially Weighted Moving Average (NEEWMA) statistic, designed to recognize slight changes in the process ...
Hina Javed, Muhammad Ismail, Nadia Saeed
doaj +1 more source
Mixed Control Charts Using EWMA Statistics
IEEE Access, 2016 In this paper, two mixed control charts are designed for process monitoring when the quality characteristic of interest follows a normal distribution.
Muhammad Aslam +3 more
doaj +1 more source