Results 71 to 80 of about 2,211,008 (287)

Dynamical Heterogeneities Below the Glass Transition

, 2001
We present molecular dynamics simulations of a binary Lennard-Jones mixture at temperatures below the kinetic glass transition. The ``mobility'' of a particle is characterized by the amplitude of its fluctuation around its average position.
A. Zippelius, Andersen, Angell, Angell, Barsky, Binder, Blackburn, Böhmer, Caprion, Caprion, Castillo, Cicerone, Cicerone, Cugliandolo, Diezemann, Doliwa, Doliwa, Donati, Donati, Ediger, Fujara, Gaukel, Gaukel, Gaukel, Gleim, Glotzer, Goldbart, Götze, Heuer, Heuer, Hurley, Hurley, Jäckle, Johnson, K. Binder, K. Vollmayr-Lee, Kanaya, Kegel, Kob, Kob, Laird, Leisen, Muranaka, Oligschleger, Oligschleger, Perera, Poole, Rahman, Richert, Richert, Russina, Schmidt, Schmidt-Rohr, Schober, Schober, Schober, Schober, Schrøder, Schrøder, Sillescu, Teichler, Vollmayr-Lee, Vollmayr-Lee, W. Kob, Weeks, Wittmer, Yamamoto, Yamamoto   +67 more
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Analytical explicit formulas of average run length for long memory process with ARFIMA model on CUSUM control chart [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2017
This paper proposes the explicit formulas for the derivation of exact formulas from Average Run Lengths (ARLs) using integral equation on CUSUM control chart when observations are long memory processes with exponential white noise. The authors compared
Wilasinee Peerajit, Yupaporn Areepong, Saowanit Sukparungsee   +2 more
doaj   +1 more source

Intergration of control chart and pattern recognizer for bivariate quality control [PDF]

, 2015
Monitoring and diagnosis of mean shifts in manufacturing processes become more challenging when involving two or more correlated variables. Unfortunately, most of the existing multivariate statistical process control schemes are only effective in rapid ...
Mohd Sohaimi, Nurul Adlihisam
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Optimal designs of the median run length based double sampling X chart for minimizing the average sample size. [PDF]

PLoS ONE, 2013
Designs of the double sampling (DS) X chart are traditionally based on the average run length (ARL) criterion. However, the shape of the run length distribution changes with the process mean shifts, ranging from highly skewed when the process is in ...
Wei Lin Teoh, Michael B C Khoo, Sin Yin Teh   +2 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Exceedance probabilities for parametric control charts [PDF]

, 2002
Common control charts assume normality and known parameters. Quite often these assumptions are not valid and large relative errors result in the usual performance characteristics, such as the false alarm rate or the average run length.
Albers, W., Kallenberg, W.C.M., Nurdiati, S.   +2 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source