Results 91 to 100 of about 4,704,446 (291)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Minimizing Bias in Selection on Observables Estimators When Unconfoundness Fails [PDF]
We characterize the bias of propensity score based estimators of common average treatment effect parameters in the case of selection on unobservables. We then propose a new minimum biased estimator of the average treatment effect.
Millimet, Daniel L., Tchernis, Rusty
core
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Causal analysis of energy retrofit for real-life cases using Average Treatment Effect [PDF]
E3S Web of ConferencesEnergy retrofit of existing buildings is one of the key strategies for achieving building decarbonization. However, its actual impact on energy reduction remains underexplored due to unobserved confounding factors.
Lee Seung-Ju +3 more
doaj +1 more source
Beyond the average treatment effect
, 2023 The overall aim of this thesis is to explore the use of baseline risk prediction models as the basis for medical decision making. We study and apply methods for the evaluation of treatment effect heterogeneity in both clinical trial data and observational data. More specifically, we systematically review the existing literature on predictive approaches
openaire +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
MODE: Minimax Optimal Deterministic Experiments for Causal Inference in the Presence of Covariates
EntropyData-driven decision-making has become crucial across various domains. Randomization and re-randomization are standard techniques employed in controlled experiments to estimate causal effects in the presence of numerous pre-treatment covariates.
Shaohua Xu, Songnan Liu, Yongdao Zhou
doaj +1 more source
Estimating average partial effects under conditional moment independence assumptions [PDF]
I show how to identify and estimate the average partial effect of explanatory variables in a model where unobserved heterogeneity interacts with the explanatory variables and may be unconditionally correlated with the explanatory variables.
Jeffrey M. Wooldridge
core
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source