Results 81 to 90 of about 4,735,813 (292)
Defining and Identifying Average Treatment Effects
American Journal of Epidemiology, 2023 Ashley I, Naimi, Brian W, Whitcomb
openaire +2 more sources
Program Evaluation and Random Program Starts [PDF]
This paper discusses the evaluation problem using observational data when the timing of treatment is an outcome of a stochastic process. We show that, without additional assumptions, it is not possible to estimate the average treatment effect and ...
Per Johansson, Peter Fredriksson
core
Automatic Debiased Machine Learning of Causal and Structural Effects
, 2020 Many causal and structural effects depend on regressions. Examples include average treatment effects, policy effects, average derivatives, regression decompositions, economic average equivalent variation, and parameters of economic structural models. The
Chernozhukov, Victor +2 more
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Local Instrumental Variables [PDF]
This paper unites the treatment effect literature and the latent variable literature. The economic questions answered by the commonly used treatment effect parameters are considered.
Edward J. Vytlacil, James J. Heckman
core
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Heterogeneous Treatment Effects with Mismeasured Endogenous Treatment
, 2017 This paper studies the identifying power of an instrumental variable in the nonparametric heterogeneous treatment effect framework when a binary treatment is mismeasured and endogenous.
Ura, Takuya
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Bounds on treatment effects on transitions [PDF]
This paper considers the definition and identification of treatment effects on conditional transition probabilities. We show that even under sequential random assignment only the instantaneous average treatment effect is point identified. Because treated
Ridder, Geert, Vikström, Johan
core
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source