Results 91 to 100 of about 4,735,813 (292)
A Class of Unbiased Estimators of the Average Treatment Effect in Randomized Experiments
Journal of Causal Inference, 2013 We derive a class of design-based estimators for the average treatment effect that are unbiased whenever the treatment assignment process is known. We generalize these estimators to include unbiased covariate adjustment using any model for outcomes that ...
Aronow Peter M., Middleton Joel A.
doaj +1 more source
Dealing with Limited Overlap in Estimation of Average Treatment Effects [PDF]
Estimation of average treatment effects under unconfounded or ignorable treatment assignment is often hampered by lack of overlap in the covariate distributions.
Guido W. Imbens +3 more
core
Complementarity and Identification
, 2016 This paper examines the identification power of assumptions that formalize the notion of complementarity in the context of a nonparametric bounds analysis of treatment response.
Twinam, Tate
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Moving the Goalposts: Addressing Limited Overlap in Estimation of Average Treatment Effects by Changing the Estimand [PDF]
Estimation of average treatment effects under unconfoundedness or exogenous treatment assignment is often hampered by lack of overlap in the covariate distributions.
Guido W. Imbens +3 more
core
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Beyond Just the Average Effect: Variation in Head Start Treatment Effects on Parenting Behavior
AERA Open, 2020 Parent engagement has been a cornerstone of Head Start since its inception in 1965. Prior studies have found evidence for small to moderate impacts of Head Start on parenting behaviors but have not considered the possibility that individual Head Start ...
Christina M. Padilla
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Beyond the average treatment effect
, 2023 The overall aim of this thesis is to explore the use of baseline risk prediction models as the basis for medical decision making. We study and apply methods for the evaluation of treatment effect heterogeneity in both clinical trial data and observational data. More specifically, we systematically review the existing literature on predictive approaches
openaire +1 more source
Sparsity Double Robust Inference of Average Treatment Effects
, 2019 Many popular methods for building confidence intervals on causal effects under high-dimensional confounding require strong "ultra-sparsity" assumptions that may be difficult to validate in practice.
Bradic, Jelena +2 more
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source