Results 51 to 60 of about 2,029,988 (242)
Byeong Yeob Choi,1 M Alan Brookhart2 1Department of Population Health Sciences, UT Health San Antonio, San Antonio, TX, USA; 2Department of Population Health Sciences, Duke University, Durham, NC, USACorrespondence: Byeong Yeob Choi, UT Health San ...
Choi BY, Brookhart MA
doaj
Information Theoretic Causal Effect Quantification
Modelling causal relationships has become popular across various disciplines. Most common frameworks for causality are the Pearlian causal directed acyclic graphs (DAGs) and the Neyman-Rubin potential outcome framework.
Aleksander Wieczorek, Volker Roth
doaj +1 more source
The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo +5 more
wiley +1 more source
Health Literacy, Self‐Efficacy and Knowledge of Sickle Cell Disease Among Caregivers
ABSTRACT Background Sickle cell disease (SCD) is a hereditary blood disorder in which abnormal haemoglobin leads to severe anaemia, painful crises and organ failure. Caregivers’ health literacy (HL) – their ability to assess, understand and apply information, and interact with healthcare professionals – is crucial for managing children with SCD, yet ...
Melanie Bruinooge +6 more
wiley +1 more source
ABSTRACT Background Leukemia is the most common childhood cancer in Mexico, and acute lymphoblastic leukemia (ALL) is the most frequent subtype. Exposure to high concentrations of benzene has been associated with ALL incidence, particularly in urban areas. This study evaluated the relationship between distance to benzene emission sources and the number
Orlando Rivera Zurita +5 more
wiley +1 more source
A Meta-Learning Approach for Estimating Heterogeneous Treatment Effects Under Hölder Continuity
Estimating heterogeneous treatment effects plays a vital role in many statistical applications, such as precision medicine and precision marketing. In this paper, we propose a novel meta-learner, termed RXlearner for estimating the conditional average ...
Zhihao Zhao, Congyang Zhou
doaj +1 more source
Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease
ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte +5 more
wiley +1 more source
Estimating Conditional Average Treatment Effects [PDF]
We consider a functional parameter called the conditional average treatment effect (CATE), designed to capture the heterogeneity of a treatment effect across subpopulations when the unconfoundedness assumption applies. In contrast to quantile regressions, the subpopulations of interest are defined in terms of the possible values of a set of continuous ...
Jason Abrevaya +2 more
openaire +1 more source
ABSTRACT Background Pediatric bone sarcoma patients and survivors may experience psychosocial challenges related to childhood cancer after their intensive, body‐altering treatment. This cross‐sectional study aimed to evaluate generic and survivor‐specific psychosocial outcomes in a national cohort of pediatric bone sarcoma patients and survivors, and ...
Hinke van der Hoek +14 more
wiley +1 more source
ABSTRACT Background Adolescents with haematological malignancies face significant emotional and relational challenges, often accompanied by difficulties in communicating their needs within the healthcare context. To address these issues, a narrative‐based psycho‐educational intervention based on the creation and prescription of Ironic Medications was ...
Marta Stoppa +7 more
wiley +1 more source

