Results 81 to 90 of about 3,664,136 (293)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A Characterization of the average tree solution for tree games [PDF]

open access: yes
For the class of tree games, a new solution called the average tree solution has been proposed recently. We provide a characterization of this solution.
Dolf Talman, Debasis Mishra
core  

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Climatic Regionalization between Yesterday and Tomorrow. Study Case: The Banat Plain [PDF]

open access: yesRomanian Review of Regional Studies, 2005
Climatic regionalization is an important activity of many Romanian and foreign researchers. This research work has been done for more than 100 years. For the last 30 years Romania has been divided into climatic domains, regions and districts, according ...
MIHAELA SOROCEAC
doaj  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The average covering tree value for directed graph games [PDF]

open access: yes, 2020
We introduce a single-valued solution concept, the so-called average covering tree value, for the class of transferable utility games with limited communication structure represented by a directed graph.
Khmelnitskaya, Anna   +2 more
core   +1 more source

Identifikasi Varietas Kayu Menggunakan Radially Average Power Spectrum Value Dan Orde Satu

open access: yesSINTECH (Science and Information Technology) Journal
Kayu merupakan material yang banyak dimanfaatkan dalam berbagai aspek kehidupan sehari-hari untuk kebutuhan manusia. Pengelompokan varietas kayu didasarkan beberapa parameter, diantaranya adalah sifat dan ciri-ciri struktur kayu.
Arya Mandiri, Soffiana Agustin
doaj   +1 more source

Resonance and Nonresonance in Terms of Average Values

open access: yesJournal of Differential Equations, 1996
The problem \(u''(t)+k^2u(t)+g(u(x))+h(x)=0\), \(x\in(0,\pi)\), \(u(0)=x(\pi)=0\) is considered where \(k\) is a positive integer, \(g:\mathbb{R}\to\mathbb{R}\) is a continuous function with at most linear growth, and \(h\in L^2[0,\pi]\). Existence results are proved.
Nkashama, M.N., Robinson, S.B.
openaire   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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