Results 91 to 100 of about 1,540,986 (287)
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Parametric Resonance in the Logistic Equation with Delay under a Two-Frequency Perturbation
Моделирование и анализ информационных систем, 2013 A logistic equation with a delay feedback circuit and with periodic perturbation of parameters is considered. The problem parameters (a coefficient of the linear growth and a delay) are chosen close to the critical values at which a cycle is bifurcated ...
N. D. Bykova +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Applying the Averaging Principle to a Logistic Equation with Rapidly Oscillating Delay
Моделирование и анализ информационных систем, 2014 The problem about the local dynamics of the logistic equation with rapidly oscillating time-periodic piecewise constant coefficient of delay was considered. It was shown that the averaged equation is a logistic equation with two delays.
N. D. Bykova, E. V. Grigorieva
doaj +1 more source
Averaging along Uniform Random Integers
, 2011 Motivated by giving a meaning to "The probability that a random integer has initial digit d", we define a URI-set as a random set E of natural integers such that each n>0 belongs to E with probability 1/n, independently of other integers. This enables us
De La Rue, Thierry, Janvresse, Élise
core +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Calculating Lyapunov Value for the Logistic Equation with Rapidly Oscillating Delay
Моделирование и анализ информационных систем, 2014 We consider the local dynamic of the logistic equation with rapidly oscillating timeperiodic piecewise constant or piecewise linear coefficient of delay.
N. D. Bykova
doaj +1 more source
A large number of functional forms have been suggested in the literature for estimating Lorenz curves that describe the relationship between income and population shares.
Duangkamon Chotikapanich +1 more
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