Results 81 to 90 of about 505,151 (317)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Growth Regressions, Principal Components and Frequentist Model Averaging [PDF]
This paper offers two innovations for empirical growth research. First, the paper discusses principal components augmented regressions to take into account all available information in well-behaved regressions.
Hlouskova, Jaroslava, Wagner, Martin
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FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Forecasting in Large Macroeconomic Panels using Bayesian Model Averaging [PDF]
This paper considers the problem of forecasting in large macroeconomic panels using Bayesian model averaging. Theoretical justifications for averaging across models, as opposed to selecting a single model, are given.
Gary Koop, Simon Potter
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Rota-Baxter operators on the polynomial algebras, integration and averaging operators [PDF]
, 2014 The concept of a Rota–Baxter operator is an algebraic abstraction of integration. Following this classical connection, we study the relationship between Rota–Baxter operators and integrals in the case of the polynomial algebra k[x] k[x] .
Guo, Li +5 more
core +1 more source
Asymptotical estimation of oscillatory integral
Lietuvos Matematikos Rinkinys, 2009 The oscillatory integral is important for averaging of weakly nonlinear differential systems. Uniformly valid for parameters estimation of the integral can be use for substantiation of averaging method for wave interaction modelling.
Aleksandras Krylovas
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Unraveling the Fortunates of the Fortunate: An Iterative Bayesian Model Averaging (IBMA) Approach [PDF]
We investigate country heterogeneity in cross-country growth regressions. In contrast to the previous literature that focuses on low-income countries, this study also highlights growth determinants in high-income (OECD) countries.
Chris Papageorgiou +2 more
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