Results 61 to 70 of about 505,151 (317)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Biofilms in porous media: development of macroscopic transport equations via volume averaging with closure for local mass equilibrium conditions [PDF]

open access: yes, 2009
In this work, we upscale a pore-scale description of mass transport in a porous medium containing biofilm to develop the relevant Darcy-scale equations.
Quintard, Michel   +4 more
core   +1 more source

On approximation of averaging operator

open access: yesLietuvos Matematikos Rinkinys, 2008
An algorithm for constructing approximations of averaging operators of quasi-periodical functions is presented in the paper. The algorithm can be used for constructinguniformly valid for a long time asymptotical solutions of differential equations with ...
Aleksandras Krylovas
doaj   +1 more source

Averaging Is Probably Not the Optimum Way of Aggregating Parameters in Federated Learning

open access: yesEntropy, 2020
Federated learning is a decentralized topology of deep learning, that trains a shared model through data distributed among each client (like mobile phones, wearable devices), in order to ensure data privacy by avoiding raw data exposed in data center ...
Peng Xiao   +3 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Macroeconomic forecasting using model averaging

open access: yes, 2009
PhDRecently, there has been a broadening concern on forecasting techniques that are applied on large data sets, since economists in business and management want to deal with the great magnitude of information. In this analysis, the issue of forecasting
Verra, Christina
core  

Growth, convergence and public investment. A Bayesian model averaging approach [PDF]

open access: yes, 2003
The aim of this study is twofold. First, the determinants of economic growth are studied among a wide set of potential variables for the Spanish provinces (NUTS3).
León González, Roberto   +4 more
core   +1 more source

Accidents with averages [PDF]

open access: yesJournal of General Internal Medicine, 1999
Managed care and saving money so often appear to be virtual synonyms that many employers think that the choice for managed care is easy. The article by Young and colleagues in this issue of JGIM provides a real-world example of what benefits specialists have known for a long time1: moving more employees into managed care is not necessarily a certain ...
openaire   +2 more sources

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

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