Results 121 to 130 of about 1,134,462 (290)

Averaging method for problems on quasiclassical asymptotics

open access: yesСовременная математика: Фундаментальные направления
The averaging method is developed for operators with rapidly oscillating coefficients, intended for use in problems of quasiclassical asymptotics and not assuming a periodic structure of coefficient oscillations.
S. Yu. Dobrokhotov, V. E. Nazaikinskii
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

moving average method

open access: yes
Citation: 'moving average method' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.14867 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Limit cycles bifurcating from the periodic orbits of the weight-homogeneous polynomial centers of weight-degree 3

open access: yesElectronic Journal of Differential Equations, 2018
In this article we obtain two explicit polynomials, whose simple positive real roots provide the limit cycles which bifurcate from the periodic orbits of a family of polynomial differential centers of order 5, when this family is perturbed inside the ...
Jaume LLibre   +2 more
doaj  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Bifurcation of limit cycles from quartic isochronous systems

open access: yesElectronic Journal of Differential Equations, 2014
This article concerns the bifurcation of limit cycles for a quartic system with an isochronous center. By using the averaging theory, it shows that under any small quartic homogeneous perturbations, at most two limit cycles bifurcate from the period ...
Linping Peng, Zhaosheng Feng
doaj  

Model Averaging for Accelerated Failure Time Models with Missing Censoring Indicators

open access: yesMathematics
Model averaging has become a crucial statistical methodology, especially in situations where numerous models vie to elucidate a phenomenon. Over the past two decades, there has been substantial advancement in the theory of model averaging. However, a gap
Longbiao Liao, Jinghao Liu
doaj   +1 more source

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