Results 111 to 120 of about 10,537,968 (352)
Molecular Oncology, EarlyView.Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef +10 more
wiley +1 more source
Pre-Averaging Based Estimation of Quadratic Variation in the Presence of Noise and Jumps: Theory, Implementation, and Empirical Evidence [PDF]
This paper provides theory as well as empirical results for pre-averaging estimators of the daily quadratic variation of asset prices. We derive jump robust inference for pre-averaging estimators, corresponding feasible central limit theorems and an ...
Mark Podolskij, Nikolaus Hautsch
core
3-dimensional Hopf bifurcation via averaging theory
, 2006 We consider the Lorenz system $\dot x = \s (y-x)$, $\dot y =rx -y-xz$ and $\dot z = -bz + xy$; and the Rossler system $\dot x = -(y+z)$, $\dot y = x +ay$ and $\dot z = b-cz + xz$. Here, we study the Hopf bifurcation which takes place at $q_{\pm}=(\pm\
J. Llibre, C. Buzzi, P. R. Silva
semanticscholar +1 more source
Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source
Periodic solutions of Lienard differential equations via averaging theory of order two
Anais da Academia Brasileira de Ciências, 2015 For ε ≠ 0sufficiently small we provide sufficient conditions for the existence of periodic solutions for the Lienard differential equations of the form x ′′ + f ( x ) x ′ + n 2 x + g ( x ) = ε 2 p 1 ( t ) + ε 3 p 2 ( t )
JAUME LLIBRE +2 more
doaj +1 more source
Molecular Oncology, EarlyView.In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
Limit cycles of the generalized Li'enard differential equation via averaging theory
Electronic Journal of Differential Equations, 2012 We apply the averaging theory of first and second order to a generalized Lienard differential equation. Our main result shows that for any $n,m geq 1$ there are differential equations $ddot{x}+f(x,dot{x})dot{x}+ g(x)=0$, with f and g polynomials of ...
Sabrina Badi, Amar Makhlouf
doaj
, 2019 The Hubble constant problem is the discrepancy between different measurements of the Hubble constant in different scales. We show that this problem can be resolved within the general relativistic framework of the perturbation theory in the inhomogeneous ...
Futamase, Toshifumi, Kasai, Masumi
core