Results 91 to 100 of about 734,652 (287)
Physical Theories with Average Symmetry
, 2013 This Letter probes the existence of physical laws invariant only in average when subjected to some transformation. The concept of a symmetry transformation is broadened to include corruption by random noise and average symmetry is introduced by considering functions which are invariant only in average under these transformations.
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Limit cycles for discontinuous generalized Lienard polynomial differential equations
Electronic Journal of Differential Equations, 2013 We divide $\mathbb{R}^2$ into sectors $S_1,\dots ,S_l$, with $l>1$ even, and define a discontinuous differential system such that in each sector, we have a smooth generalized Lienard polynomial differential equation $\ddot{x}+f_i(x)\dot{x} +g_i(x)=0$,
Jaume Llibre, Ana Cristina Mereu
doaj
Periodic solutions of Lienard differential equations via averaging theory of order two
Anais da Academia Brasileira de Ciências, 2015 For ε ≠ 0sufficiently small we provide sufficient conditions for the existence of periodic solutions for the Lienard differential equations of the form x ′′ + f ( x ) x ′ + n 2 x + g ( x ) = ε 2 p 1 ( t ) + ε 3 p 2 ( t )
JAUME LLIBRE +2 more
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Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Limit cycles of the generalized Li'enard differential equation via averaging theory
Electronic Journal of Differential Equations, 2012 We apply the averaging theory of first and second order to a generalized Lienard differential equation. Our main result shows that for any $n,m geq 1$ there are differential equations $ddot{x}+f(x,dot{x})dot{x}+ g(x)=0$, with f and g polynomials of ...
Sabrina Badi, Amar Makhlouf
doaj
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
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Maximum number of limit cycles for generalized Li'enard differential equations
Electronic Journal of Differential Equations, 2013 Applying the averaging theory of first and second order to a class of generalized polynomial Lienard differential equations, we improve the known lower bounds for the maximum number of limit cycles that this class can exhibit.
Sabrina Badi, Amar Makhlouf
doaj
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Distribution theory of the least squares averaging estimator [PDF]
Journal of Econometrics, 2013 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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