Results 91 to 100 of about 8,246 (209)

Transcriptomic Characterization of the Novel Avian-Origin Influenza A (H7N9) Virus: Specific Host Response and Responses Intermediate between Avian (H5N1 and H7N7) and Human (H3N2) Viruses and Implications for Treatment Options

mBio, 2014
A novel avian-origin H7N9 influenza A virus (IAV) emerged in China in 2013, causing mild to lethal human respiratory infections. H7N9 originated with multiple reassortment events between avian viruses and carries genetic markers of human adaptation ...
Laurence Josset, Hui Zeng, Sara M. Kelly, Terrence M. Tumpey, Michael G. Katze   +4 more
doaj   +1 more source

Integrated Analysis of microRNA-mRNA Expression in Mouse Lungs Infected With H7N9 Influenza Virus: A Direct Comparison of Host-Adapting PB2 Mutants

Frontiers in Microbiology, 2020
MicroRNAs (miRNAs) are important regulators involved in the antiviral response to influenza virus infection, however, an analytical comparison of miRNA and mRNA expression changes induced by several H7N9 host-adapting PB2 mutants remains undone.
Yanna Guo, Nan Huang, Miao Tian, Menglu Fan, Qingzheng Liu, Zhiyuan Liu, Tongtong Sun, Jingjin Huang, Huizhi Xia, Yongzhen Zhao, Jihui Ping   +10 more
doaj   +1 more source

A Rapid Review Contrasting the Evidence on Avian Influenza A(H5Nx) Clades 2.3.4.4b and 2.3.2.1c in Humans

Zoonoses and Public Health, Volume 72, Issue 7, Page 553-586, November 2025.
ABSTRACT Avian influenza viruses (AIV) circulate in wild and domestic bird populations, posing an on‐going risk for zoonotic transmission and virus adaptation to mammals and humans. The A(H5Nx) clades 2.3.2.1c and 2.3.4.4b currently circulating have caused sporadic infections in humans.
Tricia Corrin, Kaitlin M. Young, Mavra Qamar, Kusala Pussegoda, Austyn Baumeister, Nicole Atchessi, Erin Leonard, Lisa A. Waddell   +7 more
wiley   +1 more source

A Narrative Review on the Recent Insights Into the Pathogenicity and Potential Role of Middle East Respiratory Syndrome Coronavirus (MERS‐CoV) in the Emergence of “Disease X”

Health Science Reports, Volume 8, Issue 10, October 2025.
ABSTRACT Background and Aims Following the end of the COVID‐19 global emergency, concern has shifted to “Disease X,” a hypothetical, highly transmissible, and deadly pathogen, and Middle East Respiratory Syndrome Coronavirus (MERS‐CoV) is a prime candidate for this. This review explores its epidemiology, mutations, transmission, and potential to become
Zubaier Ahmed, Kazi Milenur Rahman Prattay, Sabrina Sharmin, Fatema‐Tuz‐Zohora, Asef Raj, Forhad Bin Faruk, Bagdad Ahmed, Humair Bin Md Omer, Anika Awal Omi, Fazle Rabbi, Nasiba Binte Bahar, Sumiya Sharmin Mou, Mehedi Islam, Eshaba Karim, Md. Elias Al‐Mamun   +14 more
wiley   +1 more source

Emergence of a new strain of the avian influenza A (H7N9) virus

Respiratory Investigation, 2013
The first 3 cases of infection with a novel avian-origin reassortant influenza A (H7N9) virus were identified in China between February and March 2013. The cases were characterized by rapidly progressive pneumonia, respiratory failure, and acute respiratory distress syndrome leading to fatal outcome. Up till April 30, 2013, a total of 128 cases of H7N9
openaire   +2 more sources

Complex Reassortment Dynamics of H9N2 Avian Influenza Viruses in Xinjiang, China: Implications for Zoonotic Spillover

Influenza and Other Respiratory Viruses, Volume 19, Issue 10, October 2025.
ABSTRACT Background H9N2 avian influenza viruses (AIVs) donate their genes to other subtype AIVs, posing significant threats to poultry industries and public health due to their endemicity and zoonotic potential. This study investigates the molecular evolution, reassortment, and mutations of the H9N2 isolates from the live poultry markets (LPMs) in ...
Nana Chang, Haiyang Wang, Kamila Aisaiti, Jingxia Guo, Tong Wu, Cheng Zhang, Han Du, Fei Du, Yuhai Bi, Zhenghai Ma   +9 more
wiley   +1 more source

Isolation and characteristic analysis of a novel strain H7N9 of avian influenza virus A from a patient with influenza-like symptoms in China

International Journal of Infectious Diseases, 2015
A novel H7N9 virus (A/Changsha/1/2013(H7N9)) identified through routine examination in the influenza network laboratory was analyzed retrospectively.
Faming Chen, Junhua Li, Biancheng Sun, Hong Zhang, Rusheng Zhang, Jie Yuan, Xinhua Ou, Wen Ye, Jingfang Chen, Yunzhi Liu, Yiwei Huang   +10 more
doaj   +1 more source

Deep Sequencing of H7N9 Influenza A Viruses from 16 Infected Patients from 2013 to 2015 in Shanghai Reveals Genetic Diversity and Antigenic Drift

mSphere, 2018
Influenza A virus (IAV) infections are a major public health concern, including annual epidemics, epizootic outbreaks, and pandemics. A significant IAV epizootic outbreak was the H7N9 avian influenza A outbreak in China, which was first detected in 2013 ...
Yong-Li Xiao, Lili Ren, Xi Zhang, Li Qi, John C. Kash, Yan Xiao, Fan Wu, Jianwei Wang, Jeffery K. Taubenberger   +8 more
doaj   +1 more source

Novel avian-origin influenza A (H7N9) virus in the human

Journal of the Chinese Medical Association, 2013
The recent article on the novel H7N9 bird flu is very interesting. As Tang and Chen mentioned, there are indeed many interesting considerations involving this new emerging infection. First, the possibility of human to human transmission of this new infection should be discussed. In fact, if human to human transmission occurs, a worldwide pandemic could
openaire   +2 more sources

A review on current trends in the treatment of human infection with H7N9-avian influenza A

, 2019
The H7N9 subtype of avian influenza is an enzootic and airborne virus which caused an influenza outbreak in China. Infected individuals mostly worked with poultry, suggesting H7N9 virus-infected poultry as the primary source of human infection ...
Foong Zi Xien, Lee Woon Kit, Kuan Hui En, Lian Chia Lynn, Palanisamy Sivanandy, Yeoh Tze Wei   +5 more
core   +1 more source