Results 41 to 50 of about 8,246 (209)

Tropism and innate host responses of a novel avian influenza A H7N9 virus: an analysis of ex-vivo and in-vitro cultures of the human respiratory tract [PDF]

, 2013
BACKGROUND: Since March, 2013, an avian-origin influenza A H7N9 virus has caused severe pneumonia in China. The aim of this study was to investigate the pathogenesis of this new virus in human beings.
Mok, KP, Guan, Y, Poon, LLM, Nicholls, JM, Chan, WY, Peiris, JSM, Tao, KP, Hui, PY, Chan, MCW, Chan, LY, Fong, JHM   +10 more
core   +1 more source

Genetically Related Avian Influenza H7N9 Viruses Exhibit Different Pathogenicity in Mice

Animals, 2023
Avian influenza viruses can cross species barriers and adapt to mammals. The H7N9 subtype AIV that emerged in China in 2013 caused 1568 human infections, with a mortality rate of nearly 40%. We conducted a retrospective analysis of H7N9 viruses that were
Xiaoquan Wang, Huafen Zheng, Ruyi Gao, Leyao Ren, Mingxia Jin, Zhuxing Ji, Xin Wang, Xiaolong Lu, Wenhao Yang, Min Gu, Xiaowen Liu, Shunlin Hu, Kaituo Liu, Xiufan Liu   +13 more
doaj   +1 more source

H7N9 avian influenza virus - search and re-search

Emerging Microbes & Infections, 2013
In February 2013, two patients with severe pneumonia and pulmonary dysfunction were admitted to Shanghai Fifth Hospital affiliated with Fudan University. The first patient, an 87-year-old man became ill on February 19th and died on February 27th. The second patient, also male and 27 years old, became ill on February 27th and died on March 4th.
Wen, Yu-Mei, Klenk, Hans-Dieter
openaire   +2 more sources

Research progress on human infection with avian influenza H7N9 [PDF]

Frontiers of Medicine, 2020
AbstractSince the first case of novel H7N9 infection was reported, China has experienced five epidemics of H7N9. During the fifth wave, a highly pathogenic H7N9 strain emerged. Meanwhile, the H7N9 virus continues to accumulate mutations, and its affinity for the human respiratory epithelial sialic acid 2–6 receptor has increased.
Wu, Xiaoxin, Xiao, Lanlan, Li, Lanjuan
openaire   +2 more sources

Three mutations switch H7N9 influenza to human-type receptor specificity. [PDF]

PLoS Pathogens, 2017
The avian H7N9 influenza outbreak in 2013 resulted from an unprecedented incidence of influenza transmission to humans from infected poultry. The majority of human H7N9 isolates contained a hemagglutinin (HA) mutation (Q226L) that has previously been ...
Robert P de Vries, Wenjie Peng, Oliver C Grant, Andrew J Thompson, Xueyong Zhu, Kim M Bouwman, Alba T Torrents de la Pena, Marielle J van Breemen, Iresha N Ambepitiya Wickramasinghe, Cornelis A M de Haan, Wenli Yu, Ryan McBride, Rogier W Sanders, Robert J Woods, Monique H Verheije, Ian A Wilson, James C Paulson   +16 more
doaj   +1 more source

Potential Pandemic of H7N9 Avian Influenza A Virus in Human [PDF]

Frontiers in Cellular and Infection Microbiology, 2018
Since 2013, the H7N9 avian influenza A virus (AIV) has caused human infections and to the extent of now surpassing H5N1. This raises an alarm about the potential of H7N9 to become a pandemic problem. Our compilation of the amino acid changes required for AIVs to cross the species-barrier discovers 58 that have very high proportions in both the human ...
Zhiqing Pu, Dan Xiang, Xiaobing Li, Tingting Luo, Xuejuan Shen, Robert W. Murphy, Ming Liao, Ming Liao, Yongyi Shen, Yongyi Shen   +9 more
openaire   +3 more sources

Immune derangement occurs in patients with H7N9 avian influenza [PDF]

Critical Care, 2014
Abstract Introduction Currently, little is known about the immunological characteristics of patients with avian influenza A (H7N9) virus infection. Methods The numbers and percentages of peripheral blood immune cells were measured in 27
Wu, Wei, Shi, Yu, Gao, Hainv, Liang, Weifeng, Sheng, Jifang, Li, Lanjuan   +5 more
openaire   +2 more sources

The origin of novel avian influenza A (H7N9) and mutation dynamics for its human-to-human transmissible capacity.

PLoS ONE, 2014
In February 2013, H7N9 (A/H7N9/2013_China), a novel avian influenza virus, broke out in eastern China and caused human death. It is a global priority to discover its origin and the point in time at which it will become transmittable between humans.
Jin Peng, Hao Yang, Hua Jiang, Yi-xiao Lin, Charles Damien Lu, Ya-wei Xu, Jun Zeng   +6 more
doaj   +1 more source

Two‐Dimensional Materials For Lateral Flow Assays: A Critical Review of Functional Roles and Translational Challenges

VIEW, EarlyView.
2D nanosheets, with large surface area, excellent optical/electrical properties, and high specificity, combine with lateral flow assay strips to enable rapid, readable detection, boosting the strips’ development and applications. Abstract Lateral flow assays (LFAs) are widely used for point‐of‐care diagnostics, but their detection capability remains ...
Weimin Xu, Ruping Liu, Na Gao, Jianxiao Zhu, Haowen Jiang, Shouzheng Jiao, Zhicheng Sun, Kai Shen, Gaolian Xu, Minghua Du, Ziyan Li, Yang Wang   +11 more
wiley   +1 more source

Mapping Spread and Risk of Avian Influenza A (H7N9) in China [PDF]

Scientific Reports, 2013
The outbreak of human infections with an emerging avian influenza A (H7N9) virus occurred in China in early 2013. It remains unknown what and how the underlying risk factors were involved in the bird-to-human cross-species transmission. To illustrate the dynamics of viral spread, we created a thematic map displaying the distribution of affected ...
Li-Qun Fang, Xin-Lou Li, Kun Liu, Yin-Jun Li, Hong-Wu Yao, Song Liang, Yang Yang, Zi-Jian Feng, Gregory C. Gray, Wu-Chun Cao   +9 more
openaire   +2 more sources