Results 111 to 120 of about 13,908 (226)

The Next Disease X‐ H5N6 Avian Influenza's Evolving Threat to Human Health and Chances of Future Global Outbreak: A Narrative Review

Health Science Reports, Volume 8, Issue 11, November 2025.
ABSTRACT Background and Aims H5N6 avian influenza has been a concern that can initiate the next global pandemic (called Disease X). Most infections have been among those in Asia, especially China, since the 2014 first human case. With a fatality rate of 61%, the virus is very deadly, even though the total number of human cases is relatively low.
Shoubeho Sadique Shandhi, Mosiur Rahman, Mohammad Shahriar, Ramisa Anjum   +3 more
wiley   +1 more source

The Novel Human Influenza A(H7N9) Virus Is Naturally Adapted to Efficient Growth in Human Lung Tissue

mBio, 2013
A novel influenza A virus (IAV) of the H7N9 subtype has been isolated from severely diseased patients with pneumonia and acute respiratory distress syndrome and, apparently, from healthy poultry in March 2013 in Eastern China.
Jessica Knepper, Kristina L. Schierhorn, Anne Becher, Matthias Budt, Mario Tönnies, Torsten T. Bauer, Paul Schneider, Jens Neudecker, Jens C. Rückert, Achim D. Gruber, Norbert Suttorp, Brunhilde Schweiger, Stefan Hippenstiel, Andreas C. Hocke, Thorsten Wolff   +14 more
doaj   +1 more source

Mild infection of a novel H7N9 avian influenza virus in children in Shanghai

Emerging Microbes & Infections, 2013
Dear Editor,Human infection by avian influenza virus (AIV) subtypes H71,2 and H9N23 has been reported in various countries over the past few years.
Yu, Xuelian, Zhang, Xi, He, Yi, Wu, Huanyu, Gao, Xia, Pan, Qichao, Shen, Jiaren, Zhu, Jianming, Chen, Hongyou, Zhu, Yiyi, Wu, Fan, Wang, Jianwei, Yuan, Zhengan   +12 more
openaire   +2 more sources

Comprehensive Characterization of Serum MicroRNA Profile in Response to the Emerging Avian Influenza A (H7N9) Virus Infection in Humans

Viruses, 2014
A novel avian-origin influenza A (H7N9) virus recently occurred in China and caused 137 human infection cases with a 32.8% mortality rate. Although various detection procedures have been developed, the pathogenesis of this emerging virus in humans ...
Zheng Zhu, Y. Qi, A. Ge, Yefei Zhu, Ke Xu, H. Ji, Zhi-yang Shi, L. Cui, Minghao Zhou   +8 more
semanticscholar   +1 more source

A Systematic Review of New, Enhanced Surveillance Systems and Methodologies for Zoonotic Influenza Viruses in Animals and Human–Animal Interface

Influenza and Other Respiratory Viruses, Volume 19, Issue 11, November 2025.
ABSTRACT In 2009, the World Health Organization (WHO) developed a public health research agenda for influenza to guide researchers and outline directions and priority areas for research on influenza aiming at reducing the burden of seasonal epidemic influenza and the risk and impact of pandemic influenza. The agenda was updated in 2017, but since then,
Rebecca Badra, Wenqing Zhang, John S. L. Tam, Richard Webby, Sylvie Van Der Werf, Sergejs Nikisins, Ann Cullinane, Saad Gharaibeh, Richard Njouom, Malik Peiris, Ghazi Kayali, Jean‐Michel Heraud   +11 more
wiley   +1 more source

Recombinant virus-like particles elicit protective immunity against avian influenza A(H7N9) virus infection in ferrets

Vaccine, 2015
In March 2013, diagnosis of the first reported case of human infection with a novel avian-origin influenza A(H7N9) virus occurred in eastern China. Most human cases have resulted in severe respiratory illness and, in some instances, death.
Ye V. Liu, M. Massare, Melissa B. Pearce, Xiangjie Sun, J. Belser, T. Maines, Hannah M. Creager, G. Glenn, P. Pushko, Gale Smith, T. Tumpey   +10 more
semanticscholar   +1 more source

Conservation of T cell epitopes between seasonal influenza viruses and the novel influenza A H7N9 virus

, 2014
A novel avian influenza A (H7N9) virus recently emerged in the Yangtze River delta and caused diseases, often severe, in over 130 people. This H7N9 virus appeared to infect humans with greater ease than previous avian influenza virus subtypes such as ...
Liu, Y, Wenwei Tu, Hui-Ling Yen, Yen, H, Lau, YL, Yinping Liu, Huawei Mao, Mao, H, Tu, W, Peiris, JSM, Yu-Lung Lau, J. S. Malik Peiris   +11 more
core   +1 more source

A Rapid Review Contrasting the Evidence on Avian Influenza A(H5Nx) Clades 2.3.4.4b and 2.3.2.1c in Humans

Zoonoses and Public Health, Volume 72, Issue 7, Page 553-586, November 2025.
ABSTRACT Avian influenza viruses (AIV) circulate in wild and domestic bird populations, posing an on‐going risk for zoonotic transmission and virus adaptation to mammals and humans. The A(H5Nx) clades 2.3.2.1c and 2.3.4.4b currently circulating have caused sporadic infections in humans.
Tricia Corrin, Kaitlin M. Young, Mavra Qamar, Kusala Pussegoda, Austyn Baumeister, Nicole Atchessi, Erin Leonard, Lisa A. Waddell   +7 more
wiley   +1 more source

Human infection with avian influenza A(H7N9) virus re-emerges in China in winter 2013.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2013
Through a national surveillance system for unexplained pneumonia, a severe case of influenza A(H7N9) in a man in his mid-30s was identified in Zhejiang Province, China on 14 October 2013.
E. Chen, Yuyun Chen, L. Fu, Z. Chen, Z. Gong, H. Mao, Dayan Wang, My Ni, Peng Wu, Z. Yu, T. He, Z. Li, J. Gao, Sh Liu, Y. Shu, B. Cowling, S. Xia, Hongjie Yu   +17 more
semanticscholar   +1 more source

A Narrative Review on the Recent Insights Into the Pathogenicity and Potential Role of Middle East Respiratory Syndrome Coronavirus (MERS‐CoV) in the Emergence of “Disease X”

Health Science Reports, Volume 8, Issue 10, October 2025.
ABSTRACT Background and Aims Following the end of the COVID‐19 global emergency, concern has shifted to “Disease X,” a hypothetical, highly transmissible, and deadly pathogen, and Middle East Respiratory Syndrome Coronavirus (MERS‐CoV) is a prime candidate for this. This review explores its epidemiology, mutations, transmission, and potential to become
Zubaier Ahmed, Kazi Milenur Rahman Prattay, Sabrina Sharmin, Fatema‐Tuz‐Zohora, Asef Raj, Forhad Bin Faruk, Bagdad Ahmed, Humair Bin Md Omer, Anika Awal Omi, Fazle Rabbi, Nasiba Binte Bahar, Sumiya Sharmin Mou, Mehedi Islam, Eshaba Karim, Md. Elias Al‐Mamun   +14 more
wiley   +1 more source