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Evolution of H7N9 highly pathogenic avian influenza virus in the context of vaccination

open access: yesEmerging Microbes and Infections
Human infections with the H7N9 influenza virus have been eliminated in China through vaccination of poultry; however, the H7N9 virus has not yet been eradicated from poultry. Carefully analysis of H7N9 viruses in poultry that have sub-optimal immunity may provide a unique opportunity to witness the evolution of highly pathogenic avian influenza virus ...
Xianying Zeng   +2 more
exaly   +4 more sources

Transcriptome Differences in Normal Human Bronchial Epithelial Cells in Response to Influenza A pdmH1N1 or H7N9 Virus Infection

open access: yesCells, 2022
Avian influenza A (H7N9) virus infections frequently lead to acute respiratory distress syndrome and death in humans. The emergence of H7N9 virus infections is a serious public health threat.
Tzu-Hsuan Hsieh   +6 more
doaj   +1 more source

Evaluation of Commercial Diagnostic Assays for the Specific Detection of Avian Influenza A (H7N9) Virus RNA Using a Quality-Control Panel and Clinical Specimens in China. [PDF]

open access: yesPLoS ONE, 2015
A novel avian influenza A H7N9-subtype virus emerged in China in 2013 and threatened global public health. Commercial kits that specifically detect avian influenza A (H7N9) virus RNA are urgently required to prepare for the emergence and potential ...
Dawei Shi   +10 more
doaj   +1 more source

Surveillance of Influenza A Virus and Its Subtypes in Migratory Wild Birds of Nepal. [PDF]

open access: yesPLoS ONE, 2015
Nepal boarders India and China and all three countries lie within the Central Asian Flyway for migratory birds. Novel influenza A H7N9 caused human fatalities in China in 2013.
Dibesh Karmacharya   +15 more
doaj   +1 more source

A System Based-Approach to Examine Host Response during Infection with Influenza A Virus Subtype H7N9 in Human and Avian Cells

open access: yesCells, 2020
Although the influenza A virus H7N9 subtype circulates within several avian species, it can also infect humans with a severe disease outcome. To better understand the biology of the H7N9 virus we examined the host response to infection in avian and human
Biruhalem Taye   +6 more
doaj   +1 more source

A cross-sectional study of avian influenza in one district of Guangzhou, 2013. [PDF]

open access: yesPLoS ONE, 2014
Since Feb, 2013, more than 100 human beings had been infected with novel H7N9 avian influenza virus. As of May 2013, several H7N9 viruses had been found in retail live bird markets (LBMs) in Guangdong province of southern China where several human cases ...
Haiming Zhang   +19 more
doaj   +1 more source

Avian influenza A(H7N9) virus screening in patients with fever and flu-like symptoms in a tertiary hospital in an area with confirmed cases. [PDF]

open access: yesPLoS ONE, 2013
Novel avian influenza A(H7N9) virus was isolated in fatal patients in Yangtze River Delta of China in March 2013. We aimed to screen the virus in febrile patients in a tertiary hospital in an area with confirmed cases.
Chao Wu   +12 more
doaj   +1 more source

Potential Pandemic of H7N9 Avian Influenza A Virus in Human [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2018
Since 2013, the H7N9 avian influenza A virus (AIV) has caused human infections and to the extent of now surpassing H5N1. This raises an alarm about the potential of H7N9 to become a pandemic problem. Our compilation of the amino acid changes required for AIVs to cross the species-barrier discovers 58 that have very high proportions in both the human ...
Zhiqing Pu   +9 more
openaire   +3 more sources

Research progress in human infection with avian influenza H7N9 virus [PDF]

open access: yesScience China Life Sciences, 2017
Since the identification of the novel reassortant avian influenza A (H7N9) virus in China in 2013, until Jun 30, 2017, the virus has caused five epidemic waves leading to a total of 1,552 human infections, with a fatality rate of about 40%. In the spring of 2017, highly pathogenic avian influenza (HPAI) H7N9 virus emerged and has caused 25 human ...
Jing, Tang, Dayan, Wang
openaire   +2 more sources

Supplementation of H7N9 Virus-Like Particle Vaccine With Recombinant Epitope Antigen Confers Full Protection Against Antigenically Divergent H7N9 Virus in Chickens

open access: yesFrontiers in Immunology, 2022
The continuous evolution of the H7N9 avian influenza virus suggests a potential outbreak of an H7N9 pandemic. Therefore, to prevent a potential epidemic of the H7N9 influenza virus, it is necessary to develop an effective crossprotective influenza ...
Dexin Kong   +28 more
doaj   +1 more source

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