Results 71 to 80 of about 13,908 (226)

Reverse vaccinology approach to design a novel multi-epitope subunit vaccine against avian influenza A (H7N9) virus

bioRxiv, 2018
H7N9, a novel strain of avian origin influenza was the first recorded incidence where a human was transited by a N9 type influenza virus. Effective vaccination against influenza A (H7N9) is a major concern, since it has emerged as a life threatening ...
M. Hasan, P. Ghosh, Kazi Faizul Azim, S. Mukta, R. A. Abir, J. Nahar, Mohammad Mehedi Hasan Khan   +6 more
semanticscholar   +1 more source

Structural Investigations and Binding Mechanisms of Oseltamivir Drug Resistance Conferred by the E119V Mutation in Influenza H7N9 Virus

Molecules, 2022
The use of vaccinations and antiviral medications have gained popularity in the therapeutic management of avian influenza H7N9 virus lately. Antiviral medicines are more popular due to being readily available. The presence of the neuraminidase protein in
Samuel C. Ugbaja, Sphamandla E. Mtambo, Aganze G. Mushebenge, Patrick Appiah-Kubi, Bahijjahtu H. Abubakar, Mthobisi L. Ntuli, Hezekiel M. Kumalo   +6 more
doaj   +1 more source

Three mutations switch H7N9 influenza to human-type receptor specificity. [PDF]

PLoS Pathogens, 2017
The avian H7N9 influenza outbreak in 2013 resulted from an unprecedented incidence of influenza transmission to humans from infected poultry. The majority of human H7N9 isolates contained a hemagglutinin (HA) mutation (Q226L) that has previously been ...
Robert P de Vries, Wenjie Peng, Oliver C Grant, Andrew J Thompson, Xueyong Zhu, Kim M Bouwman, Alba T Torrents de la Pena, Marielle J van Breemen, Iresha N Ambepitiya Wickramasinghe, Cornelis A M de Haan, Wenli Yu, Ryan McBride, Rogier W Sanders, Robert J Woods, Monique H Verheije, Ian A Wilson, James C Paulson   +16 more
doaj   +1 more source

Comparison of H7N9 and H9N2 influenza infections in mouse model unravels the importance of early innate immune response in host protection

Frontiers in Cellular and Infection Microbiology, 2022
The outcome of infection with influenza A virus is determined by a complex virus-host interaction. A new H7N9 virus of avian origin crossed the species barrier to infect humans, causing high mortality and emerged as a potential pandemic threat.
Cuisong Zhu, Cuisong Zhu, Miaomiao Zhang, Weihui Fu, Yongquan He, Yu Yang, Linxia Zhang, Songhua Yuan, Lang Jiang, Jianqing Xu, Jianqing Xu, Xiaoyan Zhang, Xiaoyan Zhang   +12 more
doaj   +1 more source

Effect of chlorine dioxide on avian influenza A (H7N9) virus

Biosafety and Health, 2022
Avian influenza remains a threat to human wellbeing. Hypochlorite derivatives are commonly used as disinfectants to prevent the spread of the disease. The World Health Organization (WHO) has listed chlorine dioxide (ClO2) as an A1-level, safe, and efficient disinfectant.
Zhiping Sun, Yun Qian, Norio Ogata, Xia Cai, Wendong Han, Youhua Xie, Hirofumi Morino, Koushirou Sogawa, Takashi Shibata, Di Qu   +9 more
openaire   +2 more sources

Detection of Antibodies against H5 and H7 strains in Birds: Evaluation of Influenza Pseudovirus Particle Neutralization Tests [PDF]

, 2014
Introduction: Avian influenza viruses circulate in bird populations, and it is important to maintain and uphold our knowledge of the viral strains that are currently of interest in this context.
Lundkvist, Åke,, Karlsson, Malin, Temperton, Nigel J., Lundkvist, Åke, Falk, Kerstin, Leijon, Mikael, Temperton, Nigel J, Lagerqvist, Nina, Cassmer, Michaela, Wallerström, Sofie, Moreno, Ana, Falk, Kerstin I   +11 more
core   +1 more source

Genomic Signatures for Avian H7N9 Viruses Adapting to Humans. [PDF]

PLoS ONE, 2016
An avian influenza A H7N9 virus emerged in March 2013 and caused a remarkable number of human fatalities. Genome variability in these viruses may provide insights into host adaptability.
Guang-Wu Chen, Shu-Ming Kuo, Shu-Li Yang, Yu-Nong Gong, Mei-Ren Hsiao, Yi-Chun Liu, Shin-Ru Shih, Kuo-Chien Tsao   +7 more
doaj   +1 more source

Evolved avian influenza virus (H7N9) isolated from human cases in a middle Yangtze River city in China, from February to April 2017

Heliyon, 2019
Seven cases of avian influenza A H7N9 virus infection were reported from February to April 2017 in Changsha City. Viral genome was acquired by RT-PCR, aligned with other H7N9 viruses using Clustal W, and phylogenetic trees were constructed using the ...
Huang Zheng, Ou Xinhua, Zhang Rusheng, Yao Dong, Li Lingzhi, Liu Ruchun, Li Yelan, Chen Jingfang, Sun Biancheng   +8 more
doaj   +1 more source

Probable person to person transmission of novel avian influenza A (H7N9) virus in Eastern China, 2013: epidemiological investigation

British medical journal, 2013
Objective To determine whether the novel avian influenza H7N9 virus can transmit from person to person and its efficiency. Design Epidemiological investigations conducted after a family cluster of two patients with avian H7N9 in March 2013. Setting Wuxi,
X. Qi, Y. Qian, C. Bao, Xi-ling Guo, L. Cui, F. Tang, H. Ji, Yong Huang, Pei-Quan Cai, B. Lu, Ke Xu, C. Shi, F. Zhu, Minghao Zhou, Hua Wang   +14 more
semanticscholar   +1 more source

Transcriptomic Characterization of the Novel Avian-Origin Influenza A (H7N9) Virus: Specific Host Response and Responses Intermediate between Avian (H5N1 and H7N7) and Human (H3N2) Viruses and Implications for Treatment Options

mBio, 2014
A novel avian-origin H7N9 influenza A virus (IAV) emerged in China in 2013, causing mild to lethal human respiratory infections. H7N9 originated with multiple reassortment events between avian viruses and carries genetic markers of human adaptation ...
Laurence Josset, Hui Zeng, Sara M. Kelly, Terrence M. Tumpey, Michael G. Katze   +4 more
doaj   +1 more source