Characterization of subgroup J avian Leukosis virus isolated from Chinese indigenous chickens [PDF]
In spite of the purification of the laying hens and broilers of avian leukosis virus (ALV) has made remarkable achievements, the infection of ALV was still serious in Chinese indigenous chickens.In order to assess the epidemic state of avian leukosis virus in indigenous chickens in China, 10 novel strains of ALV subgroup J (ALV-J), named JS16JH01 to ...
Fanfeng Meng +7 more
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Enhanced inhibition of Avian leukosis virus subgroup J replication by multi-target miRNAs [PDF]
Avian leukosis virus (ALV) is a major infectious disease that impacts the poultry industry worldwide. Despite intensive efforts, no effective vaccine has been developed against ALV because of mutations that lead to resistant forms. Therefore, there is a dire need to develop antiviral agents for the treatment of ALV infections and RNA interference (RNAi)
Meng Qing-Wen +4 more
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Research Progress on Pathogenesis and Prevention of Avian Leukosis Virus J Subgroup (ALV-J)
As a major retrovirus threatening global poultry farming, Avian Leukosis Virus Subgroup J (ALV-J) has expanded its host range since discovery, extending from conventional broilers to layer chickens and native breeds. Its diverse oncogenic manifestations, including myeloid leukemia, hemangiomas, and tumors of immune and visceral organs, have led to ...
Xinyu Liu, Xi Lan
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PMAIP1 promotes J subgroup avian leukosis virus replication by regulating mitochondrial function
Avian leukosis virus Subgroup J (ALV-J) exhibits high morbidity and pathogenicity, affecting approximately 20% of poultry farms. It induces neoplastic diseases and immunosuppression. Phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1), a proapoptotic mitochondrial protein in the B-cell lymphoma-2 (Bcl-2) family, plays a role in apoptosis in ...
Yongxia Zhao +8 more
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A recombinant avian leukosis virus subgroup j for directly monitoring viral infection and the selection of neutralizing antibodies. [PDF]
Avian leukosis virus subgroup J (ALV-J) has induced serious clinical outbreaks and has become a serious infectious disease of chickens in China. We describe here the creation of a recombinant ALV-J tagged with the enhanced green fluorescent protein ...
Qi Wang +10 more
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Tropism of subgroup J avian leukosis virus as detected byin situhybridization [PDF]
The HPRS-103 strain of avian retrovirus is the prototype of subgroup J avian leukosis virus (ALV-J) and causes myeloid leukosis in meat-type chickens. Using immunohistochemical detection of the viral groupspecific antigen (Gag) we have previously demonstrated that the induction of myeloid leukosis by ALV-J is associated with viral tropism for ...
Arshad, S. S. +5 more
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Myeloid Leukosis (J-virus) - An International Broiler Industry Concern
Myeloid leukosis (ML) or myelocytomatosis/myeloblastosis is caused by a retrovirus in the Avian Leukosis/Sarcoma Group of Retroviruses (ALV). This ALV subgroup J virus (ALV-J), which is identified as the etiologic agent for ML, has caused substantial ...
Gary D. Butcher, Richard D. Miles
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gga-miR-375 plays a key role in tumorigenesis post subgroup J avian leukosis virus infection.
Avian leukosis is a neoplastic disease caused in part by subgroup J avian leukosis virus J (ALV-J). Micro ribonucleic acids (miRNAs) play pivotal oncogenic and tumour-suppressor roles in tumour development and progression.
Hongxin Li +7 more
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Avian Leukosis Virus Subgroup J in Layer Chickens, China
To the Editor: In recent years, cases of avian leukosis virus subgroup J (ALV-J) infection and tumors in commercial layer chickens and breeders of egg-type chickens have been emerging in the People’s Republic of China. ALV-J was first isolated from meat-type chickens with myeloid leukosis in 1988.
Yu-Long Gao +6 more
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Global Maps of Avian Leukosis Viruses: Research Trends and Themes Based on Networking
Avian leukosis virus (ALV) has a tremendous adverse impact on the poultry industry. Since its discovery, research on different aspects of ALV have been published.
Gul Zaib, Xuming Hu, Hengmi Cui
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