Results 41 to 50 of about 1,738 (161)

gga-miR-375 plays a key role in tumorigenesis post subgroup J avian leukosis virus infection.

PLoS ONE, 2014
Avian leukosis is a neoplastic disease caused in part by subgroup J avian leukosis virus J (ALV-J). Micro ribonucleic acids (miRNAs) play pivotal oncogenic and tumour-suppressor roles in tumour development and progression.
Hongxin Li, Huiqing Shang, Dingming Shu, Huanmin Zhang, Jun Ji, Baoli Sun, Hongmei Li, Qingmei Xie   +7 more
doaj   +1 more source

Avian leukosis virus subgroup J associated with the outbreak of erythroblastosis in chickens in China [PDF]

Virology Journal, 2013
Abstract Background Emaciation, depression and lethargy were observed in two flocks of Chinese local breed and one flock of commercial layer chicken infected naturally from 2010 to 2011. The aims of this study were to diagnose.
Wang, Guihua, Jiang, Yanping, Yu, Linin, Wang, Yue, Zhao, Xiaomin, Cheng, Ziqiang   +5 more
openaire   +2 more sources

A glance over the fence: Using phylogeny and species comparison for a better understanding of antigen recognition by human γδ T‐cells

Immunological Reviews, Volume 298, Issue 1, Page 218-236, November 2020., 2020
Abstract Both, jawless and jawed vertebrates possess three lymphocyte lineages defined by highly diverse antigen receptors: Two T‐cell‐ and one B‐cell‐like lineage. In both phylogenetic groups, the theoretically possible number of individual antigen receptor specificities can even outnumber that of lymphocytes of a whole organism.
Thomas Herrmann, Mohindar Murugesh Karunakaran, Alina Suzann Fichtner   +2 more
wiley   +1 more source

Evolutionary trajectory of fish Piscine novirhabdovirus (=Viral Hemorrhagic Septicemia Virus) across its Laurentian Great Lakes history: Spatial and temporal diversification

Ecology and Evolution, Volume 10, Issue 18, Page 9740-9775, September 2020., 2020
This study analyses the evolutionary trajectory of a novel virus over its 17‐year history, examining the dynamics of its host relationships and its patterns across geographic space and evolutionary time. We sequence its entire genome and discern that the virus has significantly changed, with its original genotypes disappearing and being replaced in a ...
Carol A. Stepien, Megan D. Niner
wiley   +1 more source

Modeling pediatric medulloblastoma

Brain Pathology, Volume 30, Issue 3, Page 703-712, May 2020., 2020
Abstract Mouse models of medulloblastoma have proven to be instrumental in understanding disease mechanisms, particularly the role of epigenetic and molecular drivers, and establishing appropriate preclinical pipelines. To date, our research community has developed murine models for all four groups of medulloblastoma, each of which will be critical for
Martine F. Roussel, Jennifer L. Stripay
wiley   +1 more source

Semen extracellular vesicles mediate vertical transmission of subgroup J avian leukosis virus

Virologica Sinica, 2022
Subgroup J avian leukosis virus (ALV-J) is a highly oncogenic retrovirus that has been devastating the global poultry industry since the late 1990s. The major infection model of ALV-J is vertical transmission, which is responsible for the congenital infection of progeny from generation to generation. Increasing evidence has suggested that extracellular
Liqin Liao, Weiguo Chen, Xiangyu Zhang, Huanmin Zhang, Aijun Li, Yiming Yan, Zi Xie, Hongxing Li, Wencheng Lin, Jingyun Ma, Xinheng Zhang, Qingmei Xie   +11 more
openaire   +2 more sources

E (XSR) element contributes to the oncogenicity of Avian leukosis virus (subgroup J)

Journal of General Virology, 2006
Among the six subgroups of Avian leukosis virus (ALV) that infect chickens, subgroup J (ALV-J) was isolated from meat-type chickens where it predominantly induces myeloid leukosis (ML) and erythroblastosis (EB). The sequence of HPRS-103, the ALV-J prototype virus, shows several distinct features, one of which is the presence of a distinct hairpin stem ...
Peter M, Chesters, Lorraine P, Smith, Venugopal, Nair   +2 more
openaire   +2 more sources

Proteomics of DF-1 cells infected with avian leukosis virus subgroup J

Virus Research, 2012
Avian leukosis virus subgroup J (ALV-J) is an avian oncogenic retrovirus that has led to severe economic losses in the poultry industry in China in recent years. The pathogenesis of virus infection and virus-host interactions are still not well elucidated.
Zhongjun, Fan, Xuming, Hu, Yongpan, Zhang, Chuan, Yu, Kun, Qian, Aijian, Qin   +5 more
openaire   +2 more sources

Development and Application of Real-Time PCR for Detection of Subgroup J Avian Leukosis Virus [PDF]

Journal of Clinical Microbiology, 2013
ABSTRACT Subgroup J avian leukosis virus (ALV-J) is an avian retrovirus that causes severe economic losses in the poultry industry. The early identification and removal of virus-shedding birds are important to reduce the spread of congenital and contact infections.
Liting, Qin, Yulong, Gao, Wei, Ni, Meiyu, Sun, Yongqiang, Wang, Chunhong, Yin, Xiaole, Qi, Honglei, Gao, Xiaomei, Wang   +8 more
openaire   +2 more sources

Role of Virus-Encoded microRNAs in Avian Viral Diseases

Viruses, 2014
With total dependence on the host cell, several viruses have adopted strategies to modulate the host cellular environment, including the modulation of microRNA (miRNA) pathway through virus-encoded miRNAs.
Yongxiu Yao, Venugopal Nair
doaj   +1 more source