Results 61 to 70 of about 1,738 (161)

Molecular Detection and Genetic Characterization of Avian Leukosis Virus From Field Outbreaks in Bangladesh

Veterinary Medicine and Science, Volume 10, Issue 6, November 2024.
Histopathological examination of the liver from an avian leukosis virus (ALV)‐infected chicken reveals tissue alterations. Molecular detection confirms the presence of ALV in the liver samples. Evolutionary origin analysis traces the identified ALV strain. Mutational analysis and structural examination of the ALV envelope (Env) protein provide insights
Md. Golzar Hossain, Riman Pathan, SM Nazmul Hasan, Anandha Mozumder, Moslema Jahan Mou, Marjana Akter, Chandan Sikder, Riyan Al Islam Reshad, Roni Mia, Sukumar Saha, Tofazzal Islam, Sharmin Akter   +11 more
wiley   +1 more source

The follicle promotes the evolution of variants of avian leukosis virus subgroup J in vertical transmission

Biochemical and Biophysical Research Communications, 2020
Avian leukosis virus (ALV) is one of the main causative agent of tumor development, which brings enormous economic losses to the poultry industry worldwide. ALV can be transmitted horizontally and vertically, and the latter often give rise to more adverse pathogenicity.
Xintao Gao, Qiuchen Li, Lichun Fang, Haozhi Song, Zhizhong Cui, Fanfeng Meng, Zhifang Zhang   +6 more
openaire   +2 more sources

Integrative RNA-seq and ChIP-seq analysis unveils metabolic regulation as a conserved antiviral mechanism of chicken p53

Microbiology Spectrum
The tumor suppressor p53, primarily functioning as a transcription factor, has exhibited antiviral capabilities against various viruses in chickens, including infectious bursal disease virus (IBDV), avian leukosis virus subgroup J (ALV-J), and avian ...
Lu Cui, Xuefeng Li, Zhijie Chen, Zheyi Liu, Yu Zhang, Zongxi Han, Shengwang Liu, Hai Li   +7 more
doaj   +1 more source

CCL4 participates in the reprogramming of glucose metabolism induced by ALV-J infection in chicken macrophages

Frontiers in Microbiology, 2023
Interferon and chemokine-mediated immune responses are two general antiviral programs of the innate immune system in response to viral infections and have recently emerged as important players in systemic metabolism.
Huixian Wu, Huixian Wu, Gul Zaib, Gul Zaib, Gul Zaib, Huan Luo, Wang Guo, Ting Wu, Shutong Zhu, Chenjun Wang, Wenxian Chai, Qi Xu, Qi Xu, Hengmi Cui, Hengmi Cui, Xuming Hu, Xuming Hu, Xuming Hu   +17 more
doaj   +1 more source

Isolation, Molecular Characterisation, and Pathogenicity Analysis of a Novel Recombinant ALV‐J Strain Isolated From Chinese Hetian Chickens

Veterinary Medicine and Science, Volume 10, Issue 6, November 2024.
Reduced mortality: The isolated LY2021J strain of ALV‐J from Hetian chickens showed lower mortality despite causing severe dysplasia. Genetic similarity: LY2021J exhibited high genetic similarity to the Chinese Heilongjiang strain JS14NT01, particularly in the gp85 and pol genes, suggesting a possible common origin.
Tianyu Lei, Liyun Zhuang, Tingting Dai, Qun Niu, Yinli Bao, Weiming Lin, Cuiqin Huang, Xintian Zheng   +7 more
wiley   +1 more source

CH25H Promotes Autophagy and Regulates the Malignant Progression of Laryngeal Squamous Cell Carcinoma Through the PI3K‐AKT Pathway

Cancer Medicine, Volume 13, Issue 20, October 2024.
ABSTRACT Background Laryngeal squamous cell carcinoma (LSCC) is a type of cancer of the respiratory tract that often presents with subtle symptoms at the early stage and is susceptible to recurrence and metastasis. Materials and Methods To find out key regulatory genes involved in LSCC development, we downloaded LSCC‐related sequencing datasets for ...
Zhenfei Xiang, Senquan Yu, Yuxin Xu, Huacai Xiong, Danfei Hu, Qun Li, Zhenhua Wu   +6 more
wiley   +1 more source

MiR-125b Suppression Inhibits Apoptosis and Negatively Regulates Sema4D in Avian Leukosis Virus-Transformed Cells

Viruses, 2019
Subgroup J avian leukosis virus (ALV-J), an oncogenic retrovirus, causes hemangiomas and myeloid tumors in chickens. We previously showed that miR-125b is down-regulated in ALV-J-induced tumors.
Chaoqi Ren, Ruyu Xie, Yongxiu Yao, Mengmeng Yu, Fangfang Chang, Lixiao Xing, Yao Zhang, Yongzhen Liu, Suyan Wang, Muhammad Farooque, Yongqiang Wang, Xiaole Qi, Changjun Liu, Yanping Zhang, Hongyu Cui, Kai Li, Li Gao, Qing Pan, Venugopal Nair, Xiaomei Wang, Yulong Gao   +20 more
doaj   +1 more source

DETEKSI DINI PENYAKIT TUMOR SEL DARAH MYELOSIT LEUKOSIS MELALUI PEMERIKSAAN ULAS DARAH

Jurnal Ilmu Pertanian Indonesia, 2007
Myelocytes blood cell tumor in chicken is a disease caused by retrovirus, avian leukosis virus subgroup J (ALV-J). The virus has the same group as human retrovirus (HIV) which caused AIDS, but the avian type possesses oncogenic properties, that could ...
Dewi Ratih Agungpriyono , Hernomoadi Huminto, Sri Estuningsih, Aryani Sismin Satyaningtijas   +3 more
doaj  

Epitope Mapping of a Monoclonal Antibody against the Gp85 of Avian Leukosis Virus Subgroup J

Journal of Veterinary Medical Science, 2012
Avian leukosis virus subgroup J poses a great threat to the poultry industry in China. To reduce the economic losses, a quick method for detection of ALV-J antigen is required for diagnosis and identification of the congenitally transmitting hens. In this study, we report the production and evaluation of one monoclonal antibody (MAb) suitable for ...
SUN, Miao, YU, Duo, MO, Hongfei, CAO, Hong, CHEN, Chen, CHEN, Fuyong   +5 more
openaire   +3 more sources

Plus-strand RNA viruses hijack Musashi homolog 1 to shield viral RNA from cytoplasmic ribonuclease degradation

Journal of Virology
A successful strategy employed by RNA viruses to achieve replication is to evade host cell RNase degradation. However, the mechanisms through which plus-strand RNA viruses effectively shield viral RNA from cellular ribonuclease degradation remain unclear.
Defang Zhou, Menglu Xu, Qingjie Liu, Ruixue Xin, Gege Cui, Longying Ding, Xiaoyang Liu, Xinyue Zhang, Tianxing Yan, Jing Zhou, Shuhai He, Liangyu Yang, Bin Xiang, Ziqiang Cheng   +13 more
doaj   +1 more source