Results 81 to 90 of about 18,773,417 (184)

CH25H Promotes Autophagy and Regulates the Malignant Progression of Laryngeal Squamous Cell Carcinoma Through the PI3K‐AKT Pathway

Cancer Medicine, Volume 13, Issue 20, October 2024.
ABSTRACT Background Laryngeal squamous cell carcinoma (LSCC) is a type of cancer of the respiratory tract that often presents with subtle symptoms at the early stage and is susceptible to recurrence and metastasis. Materials and Methods To find out key regulatory genes involved in LSCC development, we downloaded LSCC‐related sequencing datasets for ...
Zhenfei Xiang, Senquan Yu, Yuxin Xu, Huacai Xiong, Danfei Hu, Qun Li, Zhenhua Wu   +6 more
wiley   +1 more source

Truncation of the NS1 protein converts a low pathogenic avian influenza virus into a strong interferon inducer in duck cells [PDF]

, 2010
The NS1 protein of influenza A viruses is known as a nonessential virulence factor inhibiting type I interferon (IFN) production in mammals and in chicken cells. Whether NS1 inhibits the induction of type I IFNs in duck cells is currently unknown.
Guérin, Jean-Luc, Volmer, Christelle, Soubiès, Sébastien, Volmer, Romain   +3 more
core   +1 more source

MiR-125b Suppression Inhibits Apoptosis and Negatively Regulates Sema4D in Avian Leukosis Virus-Transformed Cells

Viruses, 2019
Subgroup J avian leukosis virus (ALV-J), an oncogenic retrovirus, causes hemangiomas and myeloid tumors in chickens. We previously showed that miR-125b is down-regulated in ALV-J-induced tumors.
Chaoqi Ren, Ruyu Xie, Yongxiu Yao, Mengmeng Yu, Fangfang Chang, Lixiao Xing, Yao Zhang, Yongzhen Liu, Suyan Wang, Muhammad Farooque, Yongqiang Wang, Xiaole Qi, Changjun Liu, Yanping Zhang, Hongyu Cui, Kai Li, Li Gao, Qing Pan, Venugopal Nair, Xiaomei Wang, Yulong Gao   +20 more
doaj   +1 more source

Haemangiomas, leiomyosarcoma and myeloma caused by subgroup J avian leukosis virus in a commercial layer flock

, 2010
An outbreak of simultaneously occurring haemangiomas, leiomyosarcoma and myeloma was observed in a commercial layer flock in China. The sick chickens were extremely thin and dehydrated. Scattered haemangiomas were found on the claws, breast and wings. At
Xiao, Yihong, Ni, Wei, Liu, Sidang, Qin, Mei, Sun, Honglei, Yang, Feng   +5 more
core   +2 more sources

The tyrosine phosphatase SHP-2 dephosphorylated by ALV-J via its Env efficiently promotes ALV-J replication

Virulence, 2021
Avian leukosis virus subgroup J (ALV-J) generally induces hemangioma, myeloid leukosis, and immunosuppression in chickens, causing significant poultry industry economic losses worldwide. The unusual env gene of ALV-J, with low homology to other subgroups
Tuofan Li, Jing Xie, Xiaohui Yao, Jun Zhang, Chunping Li, Dan Ren, Luyuan Li, Quan Xie, Hongxia Shao, Aijian Qin, Jianqiang Ye   +10 more
doaj   +1 more source

Inhibition of avian leukosis virus subgroup J replication by miRNA targeted against env [PDF]

Virus Genes, 2013
No effective vaccine has been developed against the subgroup J avian leukosis virus (ALV-J). The genetic diversity of ALV-J might be related to the env gene, therefore, we selected conserved sequences of the env gene and designed interference sequence.
Wang, Wei, Zhang, Zai-Ping, Tian, Jin, Xiao, Zhi-Guang, Meng, Qing-Wen   +4 more
openaire   +2 more sources

Differential contribution of PB1-F2 to the virulence of highly pathogenic H5N1 influenza A virus in mammalian and avian species [PDF]

, 2011
Highly pathogenic avian influenza A viruses (HPAIV) of the H5N1 subtype occasionally transmit from birds to humans and can cause severe systemic infections in both hosts.
García-Sastre, Adolfo, García-Sastre, A., Rong Hai, Hale Benjamin G., Pena, Lindomar, Hai, Rong, John Steel, Manicassamy Balaji, Daniel R. Pérez, Pérez Daniel R., Manicassamy, Balaji, Pena, L., Benjamin G. Hale, Sutton, T., Zsuzsanna T Varga, Troy Sutton, Sutton Troy, Varga Zsuzsanna T., Hale, B.G., Varga, Zsuzsanna T, Pena Lindomar, Zsuzsanna T. Varga, Hale, Benjamin G, Balaji Manicassamy, Adolfo García-Sastre, Schmolke, M., Hai Rong, Hai, R., Daniel R Pérez, Pérez, D.R., Sutton, Troy, Steel, John, Pérez, Daniel R, Steel, J., Steel John, García-Sastre Adolfo, Manicassamy, B., Mirco Schmolke, Lindomar Pena, Benjamin G Hale, Schmolke, Mirco, Varga, Z.T., Schmolke Mirco   +42 more
core   +2 more sources

DETEKSI DINI PENYAKIT TUMOR SEL DARAH MYELOSIT LEUKOSIS MELALUI PEMERIKSAAN ULAS DARAH

Jurnal Ilmu Pertanian Indonesia, 2007
Myelocytes blood cell tumor in chicken is a disease caused by retrovirus, avian leukosis virus subgroup J (ALV-J). The virus has the same group as human retrovirus (HIV) which caused AIDS, but the avian type possesses oncogenic properties, that could ...
Dewi Ratih Agungpriyono , Hernomoadi Huminto, Sri Estuningsih, Aryani Sismin Satyaningtijas   +3 more
doaj  

Plus-strand RNA viruses hijack Musashi homolog 1 to shield viral RNA from cytoplasmic ribonuclease degradation

Journal of Virology
A successful strategy employed by RNA viruses to achieve replication is to evade host cell RNase degradation. However, the mechanisms through which plus-strand RNA viruses effectively shield viral RNA from cellular ribonuclease degradation remain unclear.
Defang Zhou, Menglu Xu, Qingjie Liu, Ruixue Xin, Gege Cui, Longying Ding, Xiaoyang Liu, Xinyue Zhang, Tianxing Yan, Jing Zhou, Shuhai He, Liangyu Yang, Bin Xiang, Ziqiang Cheng   +13 more
doaj   +1 more source

Identification and characterization of the viral interaction determinant of the subgroup A avian leukosis virus receptor

, 1995
avian leukosis virus receptor.
John A. T. Young, K Zingler, R Peters, C A Bélanger, J A Young, E Agard   +5 more
core