Results 71 to 80 of about 1,738 (161)

Difference in pathogenicity of 2 strains of avian leukosis virus subgroup J in broiler chicken

Poultry Science, 2019
Avian leukosis virus subgroup J has been found to infect many types of chickens with various genetic backgrounds. The ALV-J strain NX0101, which was isolated from broiler breeders in 2001, mainly induces the formation of myeloid cell tumors. However, strain HN10PY01, which was recently isolated from laying hens, mainly induces the formation of myeloid ...
Guihua Zhang, Yajin Qu, Yujuan Niu, Huixia Zhang, Qinqin Sun, Xingpo Liu, Yue Li, Hui Zhang, Mengda Liu   +8 more
openaire   +2 more sources

Avian leukosis virus p15 interacts with interferon regulatory factor 7 to antagonize the cGAS-STING signaling pathway and promote viral replication

Journal of Virology
Cyclic GMP-AMP synthase (cGAS) recognizes viral DNA within the cytoplasm and initiates innate antiviral response through the cGAS-STING pathway. However, viruses have evolved diverse strategies to counteract the cGAS-STING signaling pathway.
Zhouhao Cui, Kui Shen, Moru Xu, Yongxiu Yao, Hongxia Shao, Aijian Qin, Kun Qian   +6 more
doaj   +1 more source

Characterization of avian leukosis virus subgroup J isolated between 1999 and 2013 in China

Poultry Science, 2018
Avian leukosis virus subgroup J (ALV-J) has successively infected white feather chickens, layer hens, cultivated yellow chickens, and indigenous chickens; infection rates and tumorigenicity have attracted increasingly extensive attention in China. To clarify the correlation of the epidemiological phenomenon of ALV-J with the evolution of envelope ...
Jianliang, Li, Fanfeng, Meng, Weihua, Li, Yixin, Wang, Shuang, Chang, Peng, Zhao, Zhizhong, Cui   +6 more
openaire   +2 more sources

Research Progress on Pathogenesis and Prevention of Avian Leukosis Virus J Subgroup (ALV-J)

Veterinary Sciences
As a major retrovirus threatening global poultry farming, Avian Leukosis Virus Subgroup J (ALV-J) has expanded its host range since discovery, extending from conventional broilers to layer chickens and native breeds. Its diverse oncogenic manifestations,
Xinyu Liu, Xi Lan
doaj   +1 more source

lncRNA ch-MYC-AS1 restricts ALV-J replication by disrupting the ANXA2-C-Myc oncogenic axis

Microbiology Spectrum
The c-Myc oncogene is a critical regulator of viral oncogenesis and immune evasion in multiple cancers. However, its modulation by long noncoding RNAs (lncRNAs) during retroviral infection remains poorly understood. Here, we show that ch-MYC-AS1, a novel
Suyu Fan, Weiyi Zhou, Xuming Hu, Yingjie Gu, Guangzhong Peng, Yu Zhang, Wenming Zhao, Guohong Chen, Qi Xu   +8 more
doaj   +1 more source

Aberrant expression of liver microRNA in chickens infected with subgroup J avian leukosis virus

Virus Research, 2012
Subgroup J avian leukosis virus (ALV-J) is an oncogenic retrovirus primarily causing myeloid leukosis (ML) in broilers. Although ALV is well under control in a few countries including the USA, poultry industry in many parts of the world continues suffering from serious economic loss due to sporadic or widespread ALV infection, especially ALV-J ...
Hongmei, Li, Jun, Ji, Qingmei, Xie, Huiqin, Shang, Huanmin, Zhang, Xuegang, Xin, Feng, Chen, Baoli, Sun, Chunyi, Xue, Jingyun, Ma, Yingzuo, Bi   +10 more
openaire   +2 more sources

Detection and Molecular Characterization of J Subgroup Avian Leukosis Virus in Wild Ducks in China

PLoS ONE, 2014
To assess the status of avian leukosis virus subgroup J (ALV-J) in wild ducks in China, we examined samples from 528 wild ducks, representing 17 species, which were collected in China over the past 3 years. Virus isolation and PCR showed that 7 ALV-J strains were isolated from wild ducks. The env genes and the 3'UTRs from these isolates were cloned and
Xiangwei Zeng, Lanlan Liu, Ruijun Hao, Chunyan Han   +3 more
openaire   +4 more sources

Mapping the mutational landscape of an avian retrovirus envelope protein across its evolutionary trajectory.

PLoS Pathogens
Many RNA viruses exhibit error-prone replication. Continuous generation of erroneous copies accelerates evolution. Avian leukosis virus subgroup J (ALV-J), an avian oncogenic virus, is a classical model virus for studying retroviruses.
Moru Xu, Yupeng Liu, Xin Lan, Zhenyu Wang, Kun Qian, Hongxia Shao, Jinlin Huang, Jianqiang Ye, Aijian Qin   +8 more
doaj   +1 more source

Avian leukosis virus usurps the cellular SERBP1 protein to enhance its transcription and promote productive infections in avian cells

Poultry Science
: Avian leukosis virus subgroup K (ALV-K) is composed of newly emerging isolates, which cluster separately from the well-characterized subgroups A, B, C, D, E, and J in sequence analysis, and exhibits a specific host range and a unique pattern of ...
Ning Cui, Xiaoxia Han, Xiao Yang, Xiaoran Zhao, Qinghua Huang, Chuantian Xu, Shuai Su   +6 more
doaj   +1 more source

Whole-genome resequencing to explore genome‑wide single nucleotide polymorphisms and genes associated with avian leukosis virus subgroup J infection in chicken. [PDF]

3 Biotech, 2023
Li H, Chen Y.
europepmc   +1 more source