Antigenic drift in H5N1 avian influenza virus in poultry is driven by mutations in major antigenic sites of the hemagglutinin molecule analogous to those for human influenza virus [PDF]
H5N1 highly pathogenic avian influenza virus has been endemic in poultry in Egypt since 2008, notwithstanding the implementation of mass vaccination and culling of infected birds.
Arafa, Abdel +19 more
core +1 more source
Epitope Mapping of a Monoclonal Antibody against the Gp85 of Avian Leukosis Virus Subgroup J
Avian leukosis virus subgroup J poses a great threat to the poultry industry in China. To reduce the economic losses, a quick method for detection of ALV-J antigen is required for diagnosis and identification of the congenitally transmitting hens. In this study, we report the production and evaluation of one monoclonal antibody (MAb) suitable for ...
SUN, Miao +5 more
openaire +3 more sources
Cyclic GMP-AMP synthase (cGAS) recognizes viral DNA within the cytoplasm and initiates innate antiviral response through the cGAS-STING pathway. However, viruses have evolved diverse strategies to counteract the cGAS-STING signaling pathway.
Zhouhao Cui +6 more
doaj +1 more source
The production and development of H7 Influenza virus pseudotypes for the study of humoral responses against avian viruses [PDF]
In recent years, high pathogenicity avian influenza (HPAI) virus, H5N1, low pathogenicity avian influenza (LPAI) virus, H9N2, and both HPAI and LPAI H7 viruses have proved devastating for the affected economies reliant on poultry industry, and have posed
Ferrara, Francesca +7 more
core
Intra- and interspecies transmission of H7N7 highly pathogenic avian influenza virus during the avian influenza epidemic in the Netherlands in 2003 [PDF]
The poultry epidemic of H7N7 highly pathogenic avian influenza (HPAI) virus in the Netherlands in 2003 was probably the result of the introduction of an H7N7 low pathogenic avian influenza (LPAI) virus (by interspecies transmission from wild birds) and ...
Goot, J.A., van der +3 more
core
Characterization of avian leukosis virus subgroup J isolated between 1999 and 2013 in China
Avian leukosis virus subgroup J (ALV-J) has successively infected white feather chickens, layer hens, cultivated yellow chickens, and indigenous chickens; infection rates and tumorigenicity have attracted increasingly extensive attention in China. To clarify the correlation of the epidemiological phenomenon of ALV-J with the evolution of envelope ...
Jianliang, Li +6 more
openaire +2 more sources
Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase [PDF]
This work was supported by the Medical Research Council and the Scottish Funding Council.Influenza virus sialidase has an essential role in the virus’ life cycle.
Russell, Rupert James Martin +35 more
core +1 more source
Aberrant expression of liver microRNA in chickens infected with subgroup J avian leukosis virus
Subgroup J avian leukosis virus (ALV-J) is an oncogenic retrovirus primarily causing myeloid leukosis (ML) in broilers. Although ALV is well under control in a few countries including the USA, poultry industry in many parts of the world continues suffering from serious economic loss due to sporadic or widespread ALV infection, especially ALV-J ...
Hongmei, Li +10 more
openaire +2 more sources
lncRNA ch-MYC-AS1 restricts ALV-J replication by disrupting the ANXA2-C-Myc oncogenic axis
The c-Myc oncogene is a critical regulator of viral oncogenesis and immune evasion in multiple cancers. However, its modulation by long noncoding RNAs (lncRNAs) during retroviral infection remains poorly understood. Here, we show that ch-MYC-AS1, a novel
Suyu Fan +8 more
doaj +1 more source
5' avian leukosis virus sequences and osteopetrotic potential
Recombinants of Rous-associated virus-0 and Br21 have been used to localize 5' viral sequences that affect the osteopetrotic potential of avian leukosis viruses.
Reinsch, Sigrid S. +5 more
core +1 more source

