Results 41 to 50 of about 4,322 (161)

A robust and cost-effective approach to sequence and analyze complete genomes of small RNA viruses

Virology Journal, 2017
Background Next-generation sequencing (NGS) allows ultra-deep sequencing of nucleic acids. The use of sequence-independent amplification of viral nucleic acids without utilization of target-specific primers provides advantages over traditional sequencing
Kiril M. Dimitrov, Poonam Sharma, Jeremy D. Volkening, Iryna V. Goraichuk, Abdul Wajid, Shafqat Fatima Rehmani, Asma Basharat, Ismaila Shittu, Tony M. Joannis, Patti J. Miller, Claudio L. Afonso   +10 more
doaj   +1 more source

Diversity Patterns of Domestic Herbivore Viruses in China Reveal Transmission Dynamics with Disease Management Implications

Advanced Science, Volume 13, Issue 32, 9 June 2026.
This study performs pan‐viromic profiling of 14,529 samples from 5,710 domestic herbivores across five Chinese provinces, establishing the DhCN‐Virome (1,085,360 viral metagenomes). It reveals species/sample‐specific viromic signatures and cross‐species transmission dynamics, aiding unified disease control.
Yue Sun, Yong Li, Bagen Temur, Yuanqing Lin, Yuhang Liu, Le Yi, Zheng Sun, Gang Zhang, Jun Li, Yu Guo, Linchuan Li, Jinshan Cai, Wenliang Tian, Gen Meng, Lingling Jiang, Min Fang, Fuying Ding, Xuezhang Zhou, Changchun Tu, Biao He   +19 more
wiley   +1 more source

The Effect of Vaccination on the Evolution and Population Dynamics of Avian Paramyxovirus-1

PLoS Pathogens, 2010
Newcastle Disease Virus (NDV) is a pathogenic strain of avian paramyxovirus (aPMV-1) that is among the most serious of disease threats to the poultry industry worldwide. Viral diversity is high in aPMV-1; eight genotypes are recognized based on phylogenetic reconstruction of gene sequences.
Yee Ling Chong, Abinash Padhi, Peter J Hudson, Mary Poss   +3 more
openaire   +4 more sources

Respiratory Syncytial Virus Under the Lens of Structure: From Prefusion Stabilization to Next‐Generation Immunotherapies

iNew Medicine, Volume 2, Issue 2, June 2026.
This illustration integrates key concepts covered in the review, including high‐risk populations, viral structure, host entry factors, the replication cycle, and licensed antibody‐based prevention strategies. ABSTRACT Respiratory syncytial virus (RSV) is a negative‐sense RNA virus belonging to the genus Orthopneumovirus within the family Pneumoviridae.
Zekai Cheng, Qianqian Wang, Jiachen Zhang, Sandra Chiu   +3 more
wiley   +1 more source

Gamma‐irradiated Newcastle disease virus: an alternative inactivated oncolytic virotherapy

Immunology &Cell Biology, Volume 104, Issue 5, Page 473-484, May‐June 2026.
To overcome biological risks associated with using live NDV as an oncolytic therapy, we developed gamma‐NDV as a safer alternative. Using a murine model for skin cancer, we show that intratumor administration of gamma‐NDV outperformed live‐NDV in terms of reducing tumor growth and improving overall animal survival. Abstract Newcastle disease virus (NDV)
Eve V Kennedy, Yimin Chuah, Amal H Mostafa, Chloe J Gates, Jade Foeng, Todd S Norton, Shaun R McColl, Iain Comerford, Justin B Davies, Farhid Hemmatzadeh, Mohammed Alsharifi   +10 more
wiley   +1 more source

A multi-species, multi-pathogen avian viral disease outbreak event: Investigating potential for virus transmission at the wild bird – poultry interface

Emerging Microbes and Infections
A free-range organic broiler (Gallus gallus domesticus) premises in Staffordshire was infected by high pathogenicity avian influenza virus (HPAIV) H5N8 during the 2020–2021 epizootic in the United Kingdom (UK).
Scott M. Reid, Alexander M. P. Byrne, Fabian Z. X. Lean, Craig S. Ross, Andrei Pascu, Richard Hepple, Maria Dominguez, Susanne Frost, Vivien J. Coward, Alejandro Núñez, Joe James, Levon Stephan, James N. Aegerter, Ian H. Brown, Ashley C. Banyard   +14 more
doaj   +1 more source

Development of a C5‐Azidoacetamide‐Modified 4‐Amino‐2,3‐Difluorosialic Acid Activity‐Based Probe for Labeling of Influenza A Neuraminidases

ChemBioChem, Volume 27, Issue 6, 27 March 2026.
We report DFSA5Az/DFSA5bio, C5‐azidoacetamide 4‐amino‐2,3‐difluorosialic acid activity‐based probes that trap influenza A viral (IAV) neuraminidases (NA) via a stabilized covalent Tyr‐sialosyl intermediate with hour‐scale reactivation. A bioorthogonal azide enables CuAAC (or one‐step biotin) tagging for activity‐dependent Western‐blot detection at ...
Lemeng Chao, Erianna I. Alvarado‐Melendez, Katherine Marougka, Xuesheng Wu, Cornelis A. M. de Haan, Karin Strijbis, Tom Wennekes   +6 more
wiley   +1 more source

Isolation of Avian Paramyxovirus 1 from a Patient with a Lethal Case of Pneumonia [PDF]

Journal of Virology, 2007
ABSTRACT An unknown virus was isolated from a lung biopsy sample and multiple other samples from a patient who developed a lethal case of pneumonia following a peripheral blood stem cell transplant. A random PCR-based molecular screening method was used to identify the infectious agent as avian paramyxovirus 1 (APMV-1; a group encompassing ...
Scott J, Goebel, Jill, Taylor, Bradd C, Barr, Timothy E, Kiehn, Hugo R, Castro-Malaspina, Cyrus V, Hedvat, Kim A, Rush-Wilson, Cassandra D, Kelly, Stephen W, Davis, William A, Samsonoff, Kelley R, Hurst, Melissa J, Behr, Paul S, Masters   +12 more
openaire   +2 more sources

Virus shedding in co-infections of low pathogenic avian influenza virus ( H6N2 ) and lentogenic newcastle disease virus (La Sota) in Numida Meleagris [PDF]

Trakia Journal of Sciences, 2017
An experiment was conducted to evaluate the effect of a low-pathogenic H6N2 avian influenza A viral strain (LPAIV strain H6N2) on subsequent (after 3 days) vaccination with a lentogenic avian paramyxovirus serotype 1 strain La Sota (APMV-1 strain La Sota)
Iv. Zarkov, Al. Valchev
doaj   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, Volume 15, Issue 6, 9 February 2026.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source