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Avian reovirus: Structure and biology

Virus Research, 2007
Avian reoviruses are important pathogens that cause considerable losses to the poultry industry, but they have been poorly characterized at the molecular level in the past, mostly because they have been considered to be very similar to the well-studied mammalian reoviruses.
Javier, Benavente   +1 more
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Mycophenolic acid inhibits avian reovirus replication

Antiviral Research, 2004
Avian reoviruses (ARV) are economically important pathogens, especially in the poultry industry, where they cause viral arthritis and tenosynovitis. Mycophenolic acid (MPA) is an inhibitor of inosine monophosphate dehydrogenase (mainly used clinically for immunosuppression) that inhibits the replication of several viruses.
Christopher M, Robertson   +2 more
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Experimental Egg-Transmission of Avian Reovirus

Avian Diseases, 1975
Two experiments with an avian reovirus (FDO isolant), serologically identical to the Fahey-Crawley and WVU 2937 isolants, provided conclusive proof that egg-transmission can occur. In the first experiment, 4-day-old chicken embryos were inoculated into the yolk sac with serial dilutions of virus and subsequently hatched.
N A, Menendez, B W, Calnek, B S, Cowen
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Characterization of avian reovirus ribonucleic acid

Archiv f�r die gesamte Virusforschung, 1974
Double-stranded ribonucleic acid (dsRNA) isolated from avian reovirus was separated into ten segments by means of electrophoresis on polyacrylamide gels. The fractionation pattern obtained for avian reovirus RNA was not identical with that of reovirus type 3.
K, Sekiguchi, F, Koide
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The Crawley agent: An avian reovirus

Archiv f�r die gesamte Virusforschung, 1967
The Crawley virus is not inhibited by 5-iodo-deoxyuridine and resistant to lipid solvents, trypsin and acid. In tissue cultures it produces cytoplasmic inclusion bodies. Observed in thin sections with the electron microscope, it appears as a particle, about 65 mμ in size, composed of a central core, about 37 mμ, and an outer capsid.
M, Petek   +3 more
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MURINE DISEASE INDUCED BY AVIAN REOVIRUS

Australian Journal of Experimental Biology and Medical Science, 1970
SummaryMice infected neonatally by the oronasal route with an avian reovirus (Fahey‐Crawley virus) developed pathological changes in the liver similar to those caused by murine infections with mammalian reoviruses. Further changes occurred in the central nervous system, and in the lungs, where there was severe suppurative bronchopneumonia apparently ...
P A, Phillips   +2 more
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Characterization of Avian Reovirus Strain-Specific Polymorphisms

Avian Diseases, 1990
Avian reoviruses have been associated with several pathologic conditions, but correlative relationships between genotypes and specific diseases have not been demonstrated. Six avian reoviruses (883, 176, 81-5, S1133, FC, and TX) were selected for this study, and a comparative study of the pathogenic properties of the viruses in chickens, following ...
F D, Clark   +3 more
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Early Steps in Avian Reovirus Morphogenesis

2006
Avian reoviruses are important pathogens that may cause considerable economic losses in poultry farming. Their genome expresses at least eight structural and four nonstructural proteins, three of them encoded by the S1 gene. These viruses enter cells by receptor-mediated endocytosis, and acidification of virus-containing endosomes is necessary for the ...
J, Benavente, J, Martínez-Costas
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The History of Avian Reovirus

Avian Diseases, 2000
In 1957, while studying the pathogenesis of Mycoplasma synoviae, Dr. Norman Olson et al. (22), at West Virginia University, reported the isolation of an agent producing synovitis from lesions in broilers that exhibited a lack of sensitivity to chlortetracycline and furazolidone. Olson reported in 1959 (23) that this particular agent was not susceptible
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Characterization of an avian reovirus isolated in Queensland

Journal of Comparative Pathology, 1973
Abstract An avian reovirus, RAM-1, produced cytopathic changes in chicken kidney, chick embryo fibroblast and duck embryo fibroblast cell cultures. The virus could also be titrated in chicken embryos, but this method was much less sensitive than cell culture. Following yolk sac inoculation, deaths occurred in two to four days.
A, Mustaffa-Babjee   +2 more
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