Results 1 to 10 of about 19,955 (213)

Reovirus resistance in tumors mediated by elevated ISG expression: overcoming therapeutic resistance via JAK/STAT pathway modulation [PDF]

Virology Journal
Background Oncolytic viruses such as reovirus hold significant promise for cancer therapy, but their efficacy varies across tumor types due to heterogeneous tumor cell sensitivity to reovirus.
Yuxin Yang, Xiaojin Lin, Liang Chen, Yuting Fan, Xiaowei Dou, Jing Zhang, Yingchun Zhang, Dan Liang, Xing Zhao   +8 more
doaj   +2 more sources

Reovirus infection in the pigeon. [PDF]

Annales de recherches veterinaires. Annals of veterinary research, 1982
The pigeon is sisceptible to Reovirus infection since a strain has been isolated from a sick pigeon and 8p. cent of pigeons selected at random in Belgium possess specific antibodies. The strain of Reovirus isolated does not seem to be highly pathogenic for the pigeon as experimental inoculation resulted in the appearance of no symptoms except for ...
Vindevogel, Henri, Meulemans, G., Pastoret, Paul-Pierre, Schwers, Anne, Calberg-Bacq, Claire-Michelle   +4 more
openaire   +4 more sources

Transcriptome Signature of Immune Cells Post Reovirus Treatment in KRAS Mutated Colorectal Cancer

Cancer Management and Research, 2021
Elisha J Fogel,1 Avishai Samouha,1 Sanjay Goel,2 Radhashree Maitra1,2 1Department of Biology, Yeshiva University, New York, NY, 10033, USA; 2Albert Einstein College of Medicine at Montefiore Medical Center, Bronx, NY, 10461, USACorrespondence: Radhashree
Fogel EJ, Samouha A, Goel S, Maitra R
doaj  

Incidência de reovírus em algumas cidades do Rio Grande do Sul

Revista do Instituto de Medicina Tropical de São Paulo, 1984
Amostras de soros humanos coletadas nas cidades de Pelotas, Santiago e Uruguaiana, no Estado do Rio Grande do Sul, foram testadas para anticorpos inibidores da hemaglutinação contra reovírus.
Ivo Gomes de Mattos, Inguelore S. de Souza, Telmo Vidor   +2 more
doaj   +1 more source

Modulating autophagy in KRAS mutant colorectal cancer using combination of oncolytic reovirus and carbamazepine.

PLoS ONE
Oncolytic reovirus is a potential therapeutic for colorectal cancer patients with a mutant KRAS gene. Reovirus hijacks the autophagic machinery and preferentially induces apoptosis in patients with a KRAS mutation.
Aaron Shaykevich, Danbee Chae, Isaac Silverman, Sanjay Goel, Radhashree Maitra   +4 more
doaj   +1 more source

Mammalian orthoreovirus can exit cells in extracellular vesicles.

PLoS Pathogens
Several egress pathways have been defined for many viruses. Among these pathways, extracellular vesicles (EVs) have been shown to function as vehicles of non-lytic viral egress.
Sydni Caet Smith, Evan Krystofiak, Kristen M Ogden   +2 more
doaj   +1 more source

Isolation and identification of a novel goose-origin reovirus GD218 and its pathogenicity experiments

Frontiers in Veterinary Science
Since 2020, a novel goose-derived reovirus, characterized by goose hemorrhagic hepatitis, has emerged in the goose breeding industry of Guangdong province, China, leading to significant economic losses in the poultry sector.
Yuze Li, Huihu Yang, Yongkun Lu, Zhenghao Yin, Hang Xu, Kun Mei, Shujian Huang   +6 more
doaj   +1 more source

Human Melanoma and Glioblastoma Cells Express Cathepsins Supporting Reovirus Moscow Strain Infection

Viruses
This study evaluates the oncolytic potential of the Moscow strain of reovirus against human metastatic melanoma and glioblastoma cells. The Moscow strain effectively infects and replicates within human melanoma cell lines and primary glioblastoma cells ...
Yulia Ammour, Eugenia Nikolaeva, Olesya Sagimbaeva, Pavel Shamsutdinov, Anastasia Astapenko, Yulia Zhelaeva, Marina Gavrilova, Olga Susova, Aleksey Mitrofanov, Ali Bekyashev, Tatiana Nasedkina, Oxana Svitich, Evgeny Faizuloev, Vitaly Zverev   +13 more
doaj   +1 more source

The morphology of reovirus

Virology, 1962
Abstract The fine structure of the reovirus type III has been studied by electron microscopy, using the negative staining method. The virus, grown on the epithelial strain of KB neoplastic cells, has a mean diameter of 595 A and shows evidence of icosahedral shape and 5:3:2 symmetry. The particles were found to have a core, an inner layer on the core
C, VASQUEZ, P, TOURNIER
openaire   +2 more sources

Reovirus RNA is infectious

Virology, 1990
Conditions under which reovirus RNA is infectious have been worked out. In brief, single-stranded (plus-stranded, ss) and/or double-stranded (ds) RNA of reovirus serotype 3 (ST3 virus) is lipofected into L929 mouse fibroblasts together with a rabbit reticulocyte lysate in which ss or melted dsRNA has been translated.
M R, Roner, L A, Sutphin, W K, Joklik
openaire   +2 more sources