Results 261 to 270 of about 136,222 (342)

Familial ALS With p. L127S (L126S) Variant of the Cu/Zn SOD1 Gene: A Report of Two New Cases and Literature Review

open access: yesNeuropathology, Volume 45, Issue 6, December 2025.
ABSTRACT Herein, we report two autopsy cases of familial ALS with a p. L127S (L126S) SOD1 variant. Case 1 involved a 62‐year‐old woman who presented with lower‐extremity muscle weakness with lower motor neuron signs. The patient developed bulbar palsy and died of respiratory failure 9 years after onset.
Kimiko Inoue   +6 more
wiley   +1 more source

Simultaneous Knockout of Tk1‐SST and Tk1‐FFT via CRISPR/Cas9 Enhances the Natural Rubber Accumulation in Taraxacum kok‐saghyz

open access: yesPlant Biotechnology Journal, Volume 23, Issue 12, Page 5654-5676, December 2025.
ABSTRACT Taraxacum kok‐saghyz (TKS) synthesises natural rubber (NR) and inulin using sucrose as a carbon source. However, molecular mechanisms regulating inulin and NR accumulation remain largely unclear. Here, we report the generation of double‐gene homozygous mutants, 1‐sst1‐fft, by simultaneously knocking out two key genes responsible for inulin ...
Bi Qin   +13 more
wiley   +1 more source

Feed supplementation with a mixture of C1 to C12 monoacylglycerides increases chicken resistance to Salmonella Enteritidis infection. [PDF]

open access: yesPoult Sci
Faldynova M   +8 more
europepmc   +1 more source

Eye‐Targeted A20 Gene Therapy Alleviates Ischemic Retinopathy by Reducing Pathologic Neovascularization, Gliosis, and Neuronal Apoptosis

open access: yesThe FASEB Journal, Volume 39, Issue 22, 30 November 2025.
Eye‐targeted A20 gene therapy alleviates ischemic retinopathy by limiting pathologic neovascularization, reducing gliosis, and protecting from neuronal apoptosis. ABSTRACT Intravitreal administration of anti‐VEGF therapies has been highly beneficial in treating ischemic proliferative retinopathies (PR).
Sanah Essayagh   +19 more
wiley   +1 more source

Harnessing Dye-Induced Local Heating in Lipid Membranes: A Path to Near-Infrared Light-Modulated Artificial Synaptic Vesicles. [PDF]

open access: yesACS Nano
Sarker SR   +14 more
europepmc   +1 more source

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